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Artículo
Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer
(Impact Journals, 2017)
Advanced ovarian cancer is an incurable disease. Thus, novel therapies are required. We wished to identify new therapeutic targets for ovarian cancer. ShRNA screen performed in 42 ovarian cancer cell lines identified the ...
Artículo
CtIP-mediated Alternative mRNA Splicing Fine-tunes the DNA Damage Response
(Cold Spring Harbor Laboratory Press, 2021)
In order to survive to the exposure of DNA damaging agents, cells activate a complex response that coordinates the cellular metabolism, cell cycle progression, and DNA repair. Among many other events, recent evidence has ...