Now showing items 1-10 of 129
Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles
Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of protein molecules. Most commercial paramagnetic particles are synthesized by laborious and costly ...
Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution
(Public Library of Science, 2013)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, tissue growth is coupled to changes in shape and organization. A number of studies have analyzed ...
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
(MDPI AG, 2016)
Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular disorders, some cancers, diabetes, Parkinson and Alzheimer disease. Coffee consumption, however, has ...
A positioned +1 nucleosome enhances promoter-proximal pausing
(Oxford University Press, 2015)
Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free region (NFR) followed by an array of nucleosomes towards the gene body in which the first (+1) ...
CDK targets Sae2 to control DNA-end resection and homologous recombination
(Nature Publishing Group, 2008)
DNA double-strand breaks (DSBs) are repaired by two principal mechanisms: non-homologous end-joining (NHEJ) and homologous recombination (HR)1. HR is the most accurate DSB repair mechanism but is generally restricted to ...
FANCD2 facilitates replication through common fragile sites
Common fragile sites (CFSs) are genomic regions that are unstable under conditions of replicative stress. Although the characteristics of CFSs that render them vulnerable to stress are mainly associated with replication, ...