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Artículo
Dysfunction in the Cystic Fibrosis Transmembrane Regulator in Chronic Obstructive Pulmonary Disease as a Potential Target for Personalised Medicine
(MDPI, 2021-10-10)
In recent years, numerous pathways were explored in the pathogenesis of COPD in the quest for new potential therapeutic targets for more personalised medical care. In this context, the study of the cystic fibrosis transmembrane ...
Artículo
Cigarette Smoke Decreases the Maturation of Lung Myeloid Dendritic Cells
(Public Library of Science, 2016-04-08)
Background Conflicting data exist on the role of pulmonary dendritic cells (DCs) and their maturation in patients with chronic obstructive pulmonary disease (COPD). Herein, we investigated whether disease severity and ...
Artículo
Predictors of single bronchodilation treatment response for copd: an observational study with the trace database cohort
(MDPI, 2021-04-15)
Chronic obstructive pulmonary disease (COPD) patients constitute a heterogeneous population in terms of treatment response. Our objective was to identify possible predictive factors of response to treatment with single ...
Artículo
Cellular mechanisms involved in the pathogenesis of airway remodeling in chronic lung disease
(Taylor and Francis LTD, 2022)
Background: Airway epithelial cells and lung fibroblasts play an important role in the develop-ment of chronic lung disease, but the exact mechanisms responsible have not been clarified. Our objective was to investigate ...
Artículo
Inflammatory response in human lung cells stimulated with plasma from COPD patients
(Biomed Central LTD, 2022)
Background: Chronic obstructive pulmonary disease (COPD) is a condition resulting from a persistent inflammatory state in the airways even after smoking cessation. Intriguingly, the reasons behind this persistence of the ...