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Mostrando ítems 1-9 de 9
Artículo
Assessing the impact of COVID-19 on liver cancer management (CERO-19)
(Elsevier BV, 2021)
Background & Aims: The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether ...
Artículo
European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease?
(Elsevier BV, 2021)
Background & Aims: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent emerging condition that can be optimally managed through a ...
Artículo
Extracellular Vesicles as Biomarkers in Liver Disease
(MDPI, 2022-12-19)
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, including hepatocytes, hepatic stellate cells, and immune cells in normal and pathological conditions. Depending on their ...
Artículo
Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS
(Elsevier, 2020)
Background & Aims: The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, the prevalence and prognosis of ACLF in the context of AVB is unclear, ...
Artículo
Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival
(MDPI, 2022)
Objectives: More than two years into the COVID-19 pandemic, SARS-CoV-2 still remains a global public health problem. Successive waves of infection have produced new SARS-CoV-2 variants with new mutations for which the ...
Artículo
Sofosbuvir improves HCV-induced insulin resistance by blocking IRS1 degradation
(WILEY, 2021-01-12)
In the present study, we have demonstrated that sofos buvir (SOF) treatment improves systemic insulin resis tance in hepatitis C virus (HCV)-patients, and, for the first time, revealed which molecular mechanisms are ...
Artículo
Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis
(Nature Publishing Group, 2021)
Dietary fatty acids play a role in the pathogenesis of obesity-associated non-alcoholic fatty liver disease (NAFLD), which is associated with insulin resistance (IR). Fatty acid composition is critical for IR and ...
Artículo
miRNAs in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis
(Elsevier, 2018)
Background & Aims microRNAs (miRNAs) are deregulated in non-alcoholic fatty liver disease (NAFLD) and have been proposed as useful markers for the diagnosis and stratification of disease severity. We conducted a meta-analysis ...
Artículo
Role of EpCAM+ CD133+ extracellular vesicles in steatosis to steatohepatitis transition in NAFLD
(Wiley, 2023)
Background and Aims Extracellular vesicles (EVs) have emerged as a potential source of circulating biomarkers in liver disease. We evaluated circulating AV+ EpCAM+ CD133+ EVs as a potential biomarker of the transition ...