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Listar Artículos (Fisiología Médica y Biofísica) por autor "Tabares, Lucía"
Mostrando ítems 21-37 de 37
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Neuroprotective effect of adult hematopoietic stem cells in a mouse model of motoneuron degeneration
Cabanes, Carmen; Bonilla, Sonia; Tabares, Lucía; Martínez, Salvador (2007)Degenerative spinal motor diseases, like amyotrophic lateral sclerosis, are produced by progressive degeneration of ...
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Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy
Lladó, Jerònia; Caraballo Miralles, Víctor; Tabares, Lucía; Torres Benito, Laura; Cardona Rossinyol, Andrea; Olmos, Gabriel; Garcera, Ana; Solar, Rosa María (2013) -
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Preferred Sites of Exocytosis and Endocytosis Colocalize during High- But Not Lower-Frequency Stimulation in Mouse Motor Nerve Terminals
Gaffield, Michael A.; Tabares, Lucía; Betz, William J. (SOC NEUROSCIENCE, 2009)The spatial relationship of exocytosis and endocytosis in motor nerve terminals has been explored, with varied results, ...
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Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal
López Manzaneda, Mario; Fuentes Moliz, Andrea; Tabares, Lucía (Frontiers Research Foundation, 2022)Presynaptic Ca2+ regulation is critical for accurate neurotransmitter release, vesicle reloading of release sites, and ...
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Properties of Calcium and Potassium Currents of Clonal Adrenocortical Cells
López Barneo, José; Tabares, Lucía; Ureña López, Juan (1989)The ionic currents of clonal Y-1 adrenocortical cells were studied using the whole-cell variant of the patch-clamp technique. ...
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R-Roscovitine Improves Motoneuron Function in Mouse Models for Spinal Muscular Atrophy
Tejero, Rocío; Balk, Stefanie; Franco-Espin, Julio; Ojeda Orellana, Jorge; Hennlein, Luisa; Drexl, Hans; Tabares, Lucía; Jablonka, Sibylle (Elsevier, 2020-02-21)Neurotransmission defects and motoneuron degeneration are hallmarks of spinal muscular atrophy, a monogenetic disease ...
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SMN Is Physiologically Downregulated at Wild-Type Motor Nerve Terminals but Aggregates Together with Neurofilaments in SMA Mouse Models
Franco Espín, Julio; Gatius, Alaó; Armengol, José Ángel; Arumugam, Saravanan; Moradi, Mehri; Sendtner, Michael; Calderó, Jordi; Tabares, Lucía (MDPI, 2022-10-20)muscular atrophy (SMA). SMN forms the core of a protein complex localized at the cytoplasm and nuclear gems and that ...
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SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
Torres Benito, Laura; Feodora Neher, Margret; Cano, Raquel; Tabares, Lucía (2011-10-12)Low levels of the Survival Motor Neuron (SMN) protein produce Spinal Muscular Atrophy (SMA), a severe monogenetic disease ...
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Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons
Arumugam, Saravanan; Garcera, Ana; Soler, Rosa M.; Tabares, Lucía (2017-09-05)During development, motoneurons experience significant changes in their size and in the number and strength of connections ...
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Synaptic defects in spinal muscular atrophy animal models
Torres-Benito, Laura; Ruiz Laza, Rocío; Tabares, Lucía (Wiley, 2011)Proximal spinal muscular atrophy, the most frequent genetic cause of childhood lethality, is caused by homozygous loss ...
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Synaptotagmin-2, and -1, linked to neurotransmission impairment and vulnerability in Spinal Muscular Atrophy
Tejero, Rocío; López Manzaneda, Mario; Arumugam, Saravanan; Tabares, Lucía (OXFORD UNIV PRESS, 2016)Spinal muscular atrophy (SMA) is the most frequent genetic cause of infant mortality. The disease is characterized ...
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Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions
Wu, Yuan Ju; Tejero, Rocío; Arancillo, Marife; Vardar, Gülcin; Korotkova, Tatiana; Kintscher, Michael; Tabares, Lucía; Rosenmund, Christian (AMER PHYSIOLOGICAL SOC, 2015)Syntaxin 1B is important for mouse postnatal survival and proper synaptic function at the mouse neuromuscular junctions. ...
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The Active and Periactive Zone Organization and the Functional Properties of Small and Large Synapses
Cano, Raquel; Tabares, Lucía (2016-05-24)The arrival of an action potential (AP) at a synaptic terminal elicits highly synchronized quanta release. Repetitive APs ...
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The mouse levator auris longus muscle: an amenable model system to study the role of postsynaptic proteins to the maintenance and regeneration of the neuromuscular synapse
Ojeda, Jorge; Bermedo-García, Francisca; Pérez, Viviana; Mella, Jessica; Hanna, Patricia; Herzberg, Daniel; Tejero, Rocío; López Manzaneda, Mario; Tabares, Lucía; Henríquez, Juan Pablo (Frontiers Media S.A., 2020)The neuromuscular junction (NMJ) is the peripheral synapse that controls the coordinated movement of many organisms. The ...
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The spatial pattern of exocytosis and post-exocytic mobility of synaptopHluorin in mouse motor nerve terminals
Gaffield, Michael A.; Tabares, Lucía; Betz, William J. (Wiley, 2009-03)We monitored the spatial distribution of exo- and endocytosis at 37◦C in mouse motor nerve terminals expressing synaptopHluorin ...
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The synaptic vesicle protein CSP alpha prevents presynaptic degeneration
Fernández-Chacón, Rafael; Wolfel, M.; Nishimune, H.; Tabares, Lucía; Schmitz, Frank; Castellano-Munoz, M.; Rosenmund, Christian; Montesinos Gutiérrez, María Luz; Sudhof, TC (CELL PRESS, 2004-04-22)Cysteine string protein α (CSPα)—an abundant synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 ...
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Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice
Ruiz Laza, Rocío; Lin, J.; Forgie, A.; Foletti, D.; Shelton, D.; Rosenthal, A.; Tabares, Lucía (OXFORD UNIV PRESS, 2005)Spinal muscular atrophy with respiratory distress type 1 (SMARD1) is a fatal autosomal recessive disorder seen in infants. ...