• Article
  

  Antioxidant Capacity and Phenolic and Sugar Profiles of Date Fruits Extracts from Six Different Algerian Cultivars as Influenced by Ripening Stages and Extraction Systems 

  Tassoult, Malika; Kati, Djamel Edine; Fernández Prior, África; Bermúdez-Oria, Alejandra; Fernández-Bolanos, Juan; Rodríguez-Gutiérrez, Guillermo (MDPI, 2021)

  The study investigated the phenols, sugar and the antioxidant capacities of date fruit extracts obtained by organic ...

• Article
  

  Bayesian Analysis of the Effects of Olive Oil-Derived Antioxidants on Cryopreserved Buck Sperm Parameters 

  Arando Arbulu, Ander; Navas González, Francisco Javier; Bermúdez-Oria, Alejandra; Delgado Bermejo, Juan Vicente; Fernández Prior, África; Pérez-Marín, Carlos Carmelo (MDPI, 2021)

  The present study evaluates the effect of olive oil-derived antioxidants, hydroxytyrosol (HT) and 3,4-dihydroxyphenylglycol ...

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  Extra Virgin Oil Polyphenols Improve the Protective Effects of Hydroxytyrosol in an In Vitro Model of Hypoxia-Reoxygenation of Rat Brain 

  Cruz Cortés, José Pedro de la; Pérez de Algaba, Inmaculada; Martín-Aurioles, Esther; Monsalud Arrebola, María; Ortega-Hombrados, Laura; Fernández Prior, África; Verdugo, Cristina (MPDI, 2021)

  Hydroxytyrosol (HT) is the component primarily responsible for the neuroprotective effect of extra virgin olive oil (EVOO). ...

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  From Green Technology to Functional Olive Oils: Assessing the Best Combination of Olive Tree-Related Extracts with Complementary Bioactivities 

  Hernáez, Álvaro; Jaramillo, Sara; Garcia-Borrego, Aránzazu; Espejo-Calvo, Juan Antonio; Covas, María Isabel; Blanchart, Gema; Fernández Prior, África; Fitó, Montserrat (MDPI, 2021)

  Our aim was to assess the combination of olive tree-related extracts with the most favorable profile of in vitro bioactive ...

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  Synergistic Effect of 3 ',4 '-Dihidroxifenilglicol and Hydroxytyrosol on Oxidative and Nitrosative Stress and Some Cardiovascular Biomarkers in an Experimental Model of Type 1 Diabetes Mellitus 

  Cortes, JPD.; Vallejo-Carmona, L.; Arrebola, MM.; Martin-Aurioles, E.; Rodriguez-Perez, MD; Ortega-Hombrados, Laura; Fernández Prior, África; Gonzalez-Correa, JA (MDPI, 2021)

  The objective of this study was to assess a possible synergistic effect of two extra-virgin olive oil polyphenols, ...

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  Effect of the Olive Oil Extraction Process on the Formation of Complex Pectin-Polyphenols and Their Antioxidant and Antiproliferative Activities 

  Bermudez-Oria, A.; Rodriguez-Juan, E.; Rodriguez-Gutierrez, G.; Fernández Prior, África; Fernandez-Bolanos, J. (MDPI, 2021)

  The aim of this research was to investigate the interaction of phenols and pectic polysac- charides during the olive oil ...

• Article
  

  Nephroprotective Effect of the Virgin Olive Oil Polyphenol Hydroxytyrosol in Type 1-like Experimental Diabetes Mellitus: Relationships with Its Antioxidant Effect 

  Rodriguez-Perez, MD; Lopez-Villodres, JA; Arrebola, MM; Martin-Aurioles, E; Fernández Prior, África; Gonzalez-Correa, JA (MDPI AG, 2021)

  The aim of this study was to determine whether hydroxytyrosol administration prevented kidney damage in an experimental ...

• Article
  

  Acute systemic LPS-exposure impairs perivascular CSF distribution in mice 

  Manouchehrian, O.; Ramos, M.; Bachiller, Sara; Lundgaard, I.; Deierborg, T. (Biomed Central LTD, 2021)

  The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The ...

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  The effect of electroconvulsive therapy on neuroinflammation, behavior and amyloid plaques in the 5xFAD mouse model of Alzheimer's disease 

  Svensson, M; Olsson, G; Yang, YY; Bachiller, Sara; Ekemohn, M; Deierborg, T (Nature Publishing Group, 2021)

  Microglial cells are affected in Alzheimer’s disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory ...

• Article
  

  Anxiolytic-like effects of Lupinus angustifolious protein hydrolysates in alzheimer model mice 

  Santos Sánchez, Guillermo; Ponce España, Eduardo; Cruz Chamorro, Iván; López García, Juan Carlos; Álvarez López, Ana Isabel; Pedroche, Justo; Millán-Linares, María del Carmen; Millán, Francisco; Lardone, Patricia Judith; Bejarano Hernando, Ignacio; Guerrero Montávez, Juan Miguel; Carrillo Vico, Antonio (MDPI, 2021)

  Alzheimer’s disease (AD), which is characterized by a devastating and progressive loss of memory, is the principal ...

• Article
  

  Evaluation of Tenebrio molitor protein as a source of peptides for modulating physiological processes 

  Rivero Pino, Fernando; Pérez Gálvez, Raúl; Espejo Carpio, Francisco Javier; Guadix, Emilia M. (Royal Society of Chemistry, 2020)

  The increasing world population has led to the need to search for new protein sources, such as insects, the harvesting of ...

• Article
  

  Confirmation by solid-state NMR spectroscopy of a strong complex phenol-dietary fiber with retention of antioxidant activity in vitro 

  Bermúdez Oria, Alejandra; Rodríguez Gutiérrez, Guillermo; Fernández Prior, África; Knicker, Heike E.; Fernández Bolaños, Juan (Elsevier, 2020)

  The aim of this study was to prepare a complex between the olive phenolic compounds, hydroxytyrosol (HT), 3,4-dihydroxyphenylglycol ...

• Article
  

  Deep eutectic solvents improve the biorefinery of alperujo by extraction of bioactive molecules in combination with industrial thermal treatments 

  Fernández Prior, África; Charfi, Akram; Bermúdez Oria, Alejandra; Rodríguez Juan, Elisa; Fernández Bolaños, Juan; Rodríguez Gutiérrez, Guillermo (Elsevier, 2020)

  Thermal treatments are the latest developments in the olive oil biorefinery industry to extract bioactive compounds from ...

• Article
  

  New Liquid Source of Antioxidant Phenolic Compounds in the Olive Oil Industry: Alperujo Water 

  Fernández Prior, África; Pérez Fatuarte, Juan Carlos; Bermúdez Oria, Alejandra; Viera Alcaide, Isabel; Fernández Bolaños, Juan; Rodríguez Gutiérrez, Guillermo (MDPI, 2020)

  The current management of alperujo as the main solid by-product from the two-phase olive oil extraction system has led to ...

• Article
  

  Modified level of miR-376a is associated with Parkinson's disease 

  Baghi, Masoud; Rostamian Delavar, Mahsa; Yadegari, Elaheh; Peymani, Maryam; Pozo Pérez, David; Hossein Nasr-Esfahani, Mohammad; Ghaedi, Kamran (Willey, 2020)

  Parkinson's disease (PD) is a frequent progressive neurodegenerative disorder. Impaired mitochondrial function is a major ...

• Article
  

  Biogas Potential of the Side Streams Obtained in a Novel Phenolic Extraction System from Olive Mill Solid Waste 

  Fernández Prior, África; Trujillo Reyes, Ángeles; Serrano, Antonio; Rodríguez Gutiérrez, Guillermo; Reinhard, Claudio; González Fermoso, Fernando (MDPI, 2020)

  The olive oil production is an important industrial sector in many Mediterranean areas, but it is currently struggled by ...

• Article
  

  Strawberry Puree Functionalized with Natural Hydroxytyrosol: Effects on Vitamin C and Antioxidant Activity 

  Bermúdez Oria, Alejandra; Bouchal, Yougourthane; Fernández Prior, África; Vioque, Blanca; Fernández Bolaños, Juan (MDPI, 2020)

  The natural antioxidant hydroxytyrosol (HT) was used to functionalize a strawberry puree. The effect of the antioxidant ...

• Article
  

  Pembrolizumab in combination with gemcitabine for patients with HER2-negative advanced breast cancer: GEICAM/2015–04 (PANGEA-Breast) study 

  Cruz Merino, Luis de la; Gion, M.; Cruz, J.; Alonso-Romero, J. L.; Quiroga, V.; Moreno, F.; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Rojo, F. (BMC, 2023)

  Background: We evaluated a new chemoimmunotherapy combination based on the anti-PD1 monoclonal antibody pembrolizumab and ...

• Article
  

  Ketotifen is a microglial stabilizer by inhibiting secretory vesicle acidification 

  Ramírez-Ponce, M. Pilar; Flores Cordero, Juan Antonio; Barrella, Lorenzo; Alés González de la Higuera, Eva María (Elsevier, 2023)

  Aims: Microglia survey the brain environment by sensing alarm signals to provide the first line of defense against injury ...

• Article
  

  Current research on antioxidant, anti-inflammatory and anti-obesity potential of food extracts 

  Rivero-Pino, Fernando; Millán-Linares, María del Carmen; Montserrat de la Paz, Sergio (MDPI, 2023-02-27)

  The immune-inflammatory, glucose homeostasis, and antioxidant response have a crucial role in the prevention of ...

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