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  Possible involvement of the inhibition of NF-kβ factor in anti_inflammatory actions that melatonin exert on mast cells 

  Maldonado y Aibar, María Dolores; Moreno-García, H.; González Yanes, Carmen; Calvo Gutiérrez, Juan Ramón (2016-01-08)

  Melatonin is a molecule endogenously produced in a wide variety of immune cells, including mast cells (RBL-2H3). It ...

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  Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function 

  Rosillo Ramírez, María de los Ángeles; Montserrat de la Paz, Sergio; Abia, Rocío; Castejón Martínez, María Luisa; Millán Linares, María Carmen; Alarcón de la Lastra Romero, Catalina; Fernández-Bolaños Guzmán, José María; Muriana, Francisco J. G. (Royal Society of Chemistry, 2020)

  During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ...

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  Antioxidant and Immunomodulatory Properties of Chia Protein Hydrolysates in Primary Human Monocyte–Macrophage Plasticity 

  Villanueva-Lazo, Alvaro; Montserrat de la Paz, Sergio; Grao Cruces, Elena; Pedroche, Justo; Toscano, Rocío; Millán, Francisco; Millán-Linares, María del Carmen (MDPI, 2022-02-22)

  Chia (Salvia hispanica L.) seed has high potential in the development of functional food due to its protein content with ...

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  A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge 

  López Martín, Sergio; Bermúdez Pulgarín, Beatriz; Montserrat de la Paz, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (Elsevier, 2018)

  The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous ...

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  Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages 

  Cárdeno Galván, Ana; Aparicio Soto, Marina; Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; García Muriana, Francisco José; Alarcón de la Lastra Romero, Catalina (Elsevier, 2015)

  Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that ...

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  Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome 

  Montserrat de la Paz, Sergio; Naranjo, Maria C.; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José; Bermúdez Pulgarín, Beatriz (Elsevier, 2016)

  We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated ...

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  Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells 

  López Martín, Sergio; Montserrat de la Paz, Sergio; Lucas Rodríguez, Ricardo; Bermúdez Pulgarín, Beatriz; Abia González, María del Rocío; Morales, Juan C.; García Muriana, Francisco José (Elsevier, 2017)

  The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ...

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  Minor compounds from virgin olive oil attenuate LPS-induced inflammation via visfatin-related gene modulation on primary human monocytes 

  Martín Rubio, María Esther; Millán Linares, María Carmen; Naranjo, María C.; Toscano Sánchez, María del Rocío; Abia González, María del Rocío; García Muriana, Francisco José; Bermúdez Pulgarín, Beatriz; Montserrat de la Paz, Sergio (Wiley-Blackwell, 2019)

  We have analyzed the effects of minor compounds found in the unsaponifiable fraction (UF) and in the phenolic fraction ...

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  GPETAFLR, a biopeptide from Lupinus angustifolius L., protects against oxidative and inflammatory damage in retinal pigment epithelium cells 

  Millán Linares, María Carmen; Toscano Sánchez, María del Rocío; Lemus Conejo, Ana; Martín Rubio, María Esther; Pedroche Jiménez, Justo; Millán Rodríguez, Francisco; Montserrat de la Paz, Sergio (Wiley-Blackwell, 2019)

  GPETAFLR, an octapeptide released from the enzymatic hydrolysis of lupine (Lupinus angustifolius L.) protein, has demonstrated ...

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  Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages 

  Montserrat de la Paz, Sergio; Puerta Vázquez, Rocío de la; Fernández Arche, María de los Ángeles; Quílez Guerrero, Ana María; García Muriana, Francisco José; García Giménez, María Dolores; Bermúdez Pulgarín, Beatriz (Elsevier, 2015)

  Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny ...

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  Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome 

  Montserrat de la Paz, Sergio; Bermúdez Pulgarín, Beatriz; Cardelo, Magdalena P.; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José (Royal Society of Chemistry, 2016)

  Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in ...

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  Dietary fatty acids on aortic root calcification in mice with metabolic syndrome 

  Naranjo, María C.; Bermúdez Pulgarín, Beatriz; García, Indara; López Martín, Sergio; Abia González, María del Rocío; García Muriana, Francisco José; Montserrat de la Paz, Sergio (Royal Society of Chemistry, 2017)

  Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. ...

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  Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells 

  García Muriana, Francisco José; Montserrat de la Paz, Sergio; Lucas Rodríguez, Ricardo; Bermúdez Pulgarín, Beatriz; Jaramillo Carmona, Sara; Morales, Juan C.; Abia González, María del Rocío; López Martín, Sergio (Royal Society of Chemistry, 2017)

  Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass ...

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  Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes 

  Millán Linares, María Carmen; Bermúdez Pulgarín, Beatriz; Martín Rubio, María Esther; Muñoz, Ernesto; Abia, Rocio; Millán, Francisco; García Muriana, Francisco José; Montserrat de la Paz, Sergio (Royal Society of Chemistry, 2018)

  Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich ...

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  Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function 

  Bermúdez Pulgarín, Beatriz; Dahl, Tuva Borresdatter; Medina, Indira; Groeneweg, Mathijs; Holm, Sverre; Montserrat de la Paz, Sergio; Rousch, Mat; Otten, Jeroen; Herias, Veronica; Varela Pérez, Lourdes María; Biessen, Erik Anna Leonardus (Wolters Kluwer Health, 2017)

  Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic ...

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  Monitoring of Transplanted Liver Health by Quantification of Organ-Specific Genomic Marker in Circulating DNA from Receptor 

  Macher, Hada; Suárez Artacho, Gonzalo; Guerrero Montávez, Juan Miguel; Gómez Bravo, Miguel Ángel; Álvarez Gómez, Sara; Bernal Bellido, Carmen; Domínguez Pascual, Inmaculada; Rubio Calvo, Amalia Macarena (PLOS, 2014)

  Background: Health assessment of the transplanted organ is very important due to the relationship of long-term survival ...

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  Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation 

  Roodveldt, Cintia; Labrador Garrido, Adahir; González Rey, Elena; Lachaud, Christian; Guilliams, Tim; Fernández Montesinos, Rafael; Benítez Rondan, Alicia; Robledo, Gema; Hmadcha, Abdelkrim; Delgado, Mario; Dobson, Christopher M.; Pozo, D. (PLOS, 2013)

  In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, ...

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  Obesity-associated metabolic disturbances reverse the antioxidant and anti-inflammatory properties of high-density lipoproteins in microglial cells 

  Grao Cruces, Elena; Millán Linares, María Carmen; Martín Rubio, María Esther; Toscano Sánchez, María del Rocío; Barrientos Trigo, Sergio; Bermúdez Pulgarín, Beatriz; Montserrat de la Paz, Sergio (Multidisciplinary Digital Publishing Institute (MDPI), 2021)

  High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, ...

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  Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE−/− Mice 

  Santos-Sánchez, Guillermo; Cruz-Chamorro, Ivan; Álvarez-Ríos, Ana Isabel; Lardone, Patricia Judith; Guerrero Montávez, Juan Miguel; Bejarano Hernando, Ignacio; Carrillo Vico, Antonio (MDPI, 2021-07-29)

  Metabolic-associated fatty liver disease (MAFLD) is the most important cause of liver disease worldwide. It is characterized ...

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  Identification and characterization of novel antioxidant protein hydrolysates from kiwicha (amaranthus caudatus l.) 

  Montserrat de la Paz, Sergio; Martínez‐López, Alicia; Villanueva‐Lazo, Álvaro; Pedroche, Justo; Millán, Francisco; Millán-Linares, María del Carmen (MDPI, 2021-04-22)

  : Kiwicha (Amaranthus caudatus) is considered one of the few multipurpose pseudocereals for its potential use not only ...

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