Artículos (Bioquímica Médica y Biología Molecular e Inmunología)
Recent Submissions
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altered expression of cD300a inhibitory receptor on cD4+ T cells From human immunodeficiency Virus-1-infected Patients: association With Disease Progression Markers. [Article]
(2018-07-23)The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule. Within human CD4+ T lymphocytes from ...
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Repeat Instability in the Fragile X-Related Disorders: Lessons from a Mouse Model [Article]
(Multidisciplinary Digital Publishing Institute (MDPI), 2019-03-01)The fragile X-related disorders (FXDs) are a group of clinical conditions that result primarily from an unusual mutation, the expansion of a CGG-repeat tract in exon 1 of the FMR1 gene. Mouse models are proving useful for ...
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Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-βInduced Neuronal Death [Article]
(IOS Press, 2016)Astrocytes actively participate in neuro-inflammatory processes associated to Alzheimer’s disease (AD), and other brain pathologies. We recently showed that an astrocyte-specific intracellular signaling pathway involving ...
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Aplicación de un ciclo de mejora de la docencia en la asignatura Bioquímica Humana [Article]
(Universidad de Sevilla, 2018)Se presenta una experiencia de mejora en la asignatura Bioquímica Humana en el Grado en Bioquímica, en concreto en dos temas teóricos de la asignatura. En este trabajo se propone un cambio en el modelo metodológico ...
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PGC-1alfa controls mitochondrial biogenesis and dynamics in lead-induced neurotoxicity [Article]
(Impact Journals LLC, 2015-04-09)Due to its role in regulation of mitochondrial function, PGC1α is emerging as an important player in ageing and neurodegenerative disorders. PGC1α exerts its neuroprotective effects by promoting mitochondrial biogenesis ...
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Commentary: Immunochemical Markers of the Amyloid Cascade in the Hippocampus in Motor Neuron Diseases [Article]
(Frontiers Media, 2017)In case we needed reminding, age-related neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and motor neurone disease (MND) have two factors in common: (i) advancing age as the single ...
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Role of Sam68 in post-transcriptional gene regulation [Article]
(MDPI AG, 2013-11-28)The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology ...
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Actitudes del personal sanitario hacia la donación de órganos [Article]
(Universidad Miguel Hernández. Departamento de Psicología de la Salud, 1993)En el presente artículo se realiza un estudio de la literatura sobre las actitudes del personal sanitario hacia la donación de órganos. En concreto, las disonancias entre actitudes y comportamientos y algunos factores que ...
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Newborn Screening for Primary T- and B-Cell Immune Deficiencies—A Prospective Study in Andalucía [Article]
(MDPI, 2017)Background: Quantification of T-cell-receptor-excision circles (TRECs) and kappa-deleting-recombination-excision circles (KRECs) from dried blood spots (DBS) allows detection of neonates with severe T-cell and/or B-cell ...
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Emerging topics in FXTAS [Article]
(BioMed Central, 2014-07-30)This paper summarizes key emerging issues in fragile X-associated tremor/ataxia syndrome (FXTAS) as presented at the First International Conference on the FMR1 Premutation: Basic Mechanisms & Clinical Involvement in 2013.
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Vasoactive intestinal peptide induces cell cycle arrest and regulatory functions in human T cells at multiple levels [Article]
(American Society for Microbiology, 2010-05)Vasoactive intestinal peptide (VIP) is a potent anti-inflammatory neuropeptide that, by inhibiting Th1-driven responses and inducing the emergence of regulatory T cells (Treg), has been proven successful in the induction ...
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Histomorphogenesis and immunohistochemical study of the bovine pineal gland (Bos taurus) during prenatal development (160 days of gestation to birth) [Article]
(Universidad de Murcia. Departamento de Biología Celular e Histología, 2006-10-01)The ontogenesis of the pineal gland of 20 bovine embryos (Bos taurus) has been analysed from 160 days of gestation to birth by means of optical microscopy and immunohistochemical techniques. For this study, the specimens ...
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Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production [Article]
(Rockefeller University Press, 1999-12-06)Interleukin (IL)-1 b is a pleiotropic cytokine implicated in a variety of activities, including damage of insulin-producing cells, brain injury, or neuromodulatory responses. Many of these effects are mediated by nitric ...
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Binding of [125I]Iodocyanopindolol by Rat Harderian Gland Crude Membranes: Kinetic Characteristics and Day-Night Variations [Article]
(Biochemical Society, 1996-10-01)The Harderian glands are innervated by sympathetic fibers originating in the superior cervical ganglia. The aim of this study is to characterize the /3-adrenergic receptors in the rat Harderian gland. The characteristics ...
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El hacer profesional en el aula [Article]
(Universidad de Sevilla, 1999)Esta actividad de innovación docente, fue realizada con 50 estudiantes universitarios de la Escuela de Enfermeria del Hospital de Valme y tuvo como objetivo, entrenar a los alumnos en la resolución de problemas clínicos, ...
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Metaetnografía, sentido pedagógico de actos cotidianos [Article]
(Universidad de Sevilla, 2001) -
Metaevaluación: un inquietante modelo [Article]
(Universidad de Sevilla, 2001) -
Melatonin: buffering the immune system [Article]
(2013) -
Role of leptin in the activation of immune cells [Article]
(2010) -