Artículos (Bioquímica Médica y Biología Molecular e Inmunología)
Recent Submissions
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Possible involvement of the inhibition of NF-kβ factor in anti_inflammatory actions that melatonin exert on mast cells
(2016-01-08)Melatonin is a molecule endogenously produced in a wide variety of immune cells, including mast cells (RBL-2H3). It ...
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Oleuropein and its peracetylated derivative negatively regulate osteoclastogenesis by controlling the expression of genes involved in osteoclast differentiation and function
(Royal Society of Chemistry, 2020)During chronic inflammation, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ...
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Antioxidant and Immunomodulatory Properties of Chia Protein Hydrolysates in Primary Human Monocyte–Macrophage Plasticity
(MDPI, 2022-02-22)Chia (Salvia hispanica L.) seed has high potential in the development of functional food due to its protein content with ...
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A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous ...
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Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that ...
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Olive oil, compared to a saturated dietary fat, has a protective role on atherosclerosis in niacin-treated mice with metabolic syndrome
(Elsevier, 2016)We aimed to investigate the impact of high-fat low-cholesterol diets rich in saturated fatty acids (HFLCD-SFAs), monounsaturated ...
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Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative ...
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Minor compounds from virgin olive oil attenuate LPS-induced inflammation via visfatin-related gene modulation on primary human monocytes
(Wiley-Blackwell, 2019)We have analyzed the effects of minor compounds found in the unsaponifiable fraction (UF) and in the phenolic fraction ...
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GPETAFLR, a biopeptide from Lupinus angustifolius L., protects against oxidative and inflammatory damage in retinal pigment epithelium cells
(Wiley-Blackwell, 2019)GPETAFLR, an octapeptide released from the enzymatic hydrolysis of lupine (Lupinus angustifolius L.) protein, has demonstrated ...
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Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages
(Elsevier, 2015)Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny ...
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Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in ...
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Dietary fatty acids on aortic root calcification in mice with metabolic syndrome
(Royal Society of Chemistry, 2017)Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. ...
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Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass ...
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Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes
(Royal Society of Chemistry, 2018)Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich ...
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Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
(Wolters Kluwer Health, 2017)Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic ...
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Monitoring of Transplanted Liver Health by Quantification of Organ-Specific Genomic Marker in Circulating DNA from Receptor
(PLOS, 2014)Background: Health assessment of the transplanted organ is very important due to the relationship of long-term survival ...
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Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
(PLOS, 2013)In recent years, it has become accepted that α-synuclein (αSyn) has a key role in the microglia-mediated neuroinflammation, ...
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Obesity-associated metabolic disturbances reverse the antioxidant and anti-inflammatory properties of high-density lipoproteins in microglial cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, ...
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Lupinus angustifolius Protein Hydrolysates Reduce Abdominal Adiposity and Ameliorate Metabolic Associated Fatty Liver Disease (MAFLD) in Western Diet Fed-ApoE−/− Mice
(MDPI, 2021-07-29)Metabolic-associated fatty liver disease (MAFLD) is the most important cause of liver disease worldwide. It is characterized ...
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Identification and characterization of novel antioxidant protein hydrolysates from kiwicha (amaranthus caudatus l.)
(MDPI, 2021-04-22): Kiwicha (Amaranthus caudatus) is considered one of the few multipurpose pseudocereals for its potential use not only ...