Buscar
Mostrando ítems 1-10 de 14
Artículo
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration
(CSIC, 2017)
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management. ...
Artículo
A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous pathological conditions. Exaggerated and prolonged states of postprandial hypertriglyceridemia are ...
Artículo
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate ...
Artículo
Tyrosol and its metabolites as antioxidative and anti-inflammatory molecules in human endothelial cells
(Royal Society of Chemistry, 2017)
Tyrosol (Tyr) is a phenolic compound found in virgin olive oil. After ingestion, Tyr undergoes extensive first pass intestinal/hepatic metabolism. However, knowledge about the biological effects of Tyr metabolites is scarce. ...
Artículo
Dietary fatty acids on aortic root calcification in mice with metabolic syndrome
(Royal Society of Chemistry, 2017)
Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. The aim of this study was to determine the role of high-fat low-cholesterol diets (HFLCDs) rich in ...
Artículo
Minor compounds from virgin olive oil attenuate LPS-induced inflammation via visfatin-related gene modulation on primary human monocytes
(Wiley-Blackwell, 2019)
We have analyzed the effects of minor compounds found in the unsaponifiable fraction (UF) and in the phenolic fraction (PF) of virgin olive oil (VOO) on LPS-induced inflammatory response via visfatin modulation in human ...
Artículo
Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes
(Royal Society of Chemistry, 2018)
Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich source of bioactive compounds. Herein, we report that the unsaponifiable fraction (UF) isolated from ...
Artículo
Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic ...
Artículo
Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
(Wolters Kluwer Health, 2017)
Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic effects, whereas the role of intracellular NAMPT (iNAMPT), the rate limiting enzyme in the salvage ...
Artículo
Squalene targets pro- and anti-inflammatory mediators and pathways to modulate over-activation of neutrophils, monocytes and macrophages
(Elsevier, 2015)
Squalene is a natural triterpene consumed as an integral part of the human diet. Increasing evidence demonstrates that squalene has antioxidant, cardioprotective and anti-carcinogenic activities. Nevertheless, its ...