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Mostrando ítems 1-10 de 57
Artículo
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration
(CSIC, 2017)
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management. ...
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Role of Sam68 in post-transcriptional gene regulation
(MDPI AG, 2013-11-28)
The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology ...
Artículo
Blockade of the Interaction of Calcineurin with FOXO in Astrocytes Protects Against Amyloid-βInduced Neuronal Death
(IOS Press, 2016)
Astrocytes actively participate in neuro-inflammatory processes associated to Alzheimer’s disease (AD), and other brain pathologies. We recently showed that an astrocyte-specific intracellular signaling pathway involving ...
Artículo
A microRNA expression signature of the postprandial state in response to a high-saturated-fat challenge
(Elsevier, 2018)
The postprandial hypertriglyceridemia is an important and largely silent disturbance involved in the genesis of numerous pathological conditions. Exaggerated and prolonged states of postprandial hypertriglyceridemia are ...
Artículo
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
(Elsevier, 2017)
The effects of chemically synthesized metabolites (sulfate and glucuronate forms) from hydroxytyrosol (HTyr) on oxidative stress and inflammation were investigated in TNF-α-activated human endothelial cells. HTyr sulfate ...
Artículo
Artículo
Emerging topics in FXTAS
(BioMed Central, 2014-07-30)
This paper summarizes key emerging issues in fragile X-associated tremor/ataxia syndrome (FXTAS) as presented at the First International Conference on the FMR1 Premutation: Basic Mechanisms & Clinical Involvement in 2013.
Artículo
Differential Interactome and Innate Immune Response Activation of Two Structurally Distinct Misfolded Protein Oligomers
(American Chemical Society, 2019)
The formation of misfolded protein oligomers during early stages of amyloid aggregation and the activation of neuroinflammatory responses are two key events associated with neurodegenerative diseases. Although it has been ...
Artículo
Aplicación de un ciclo de mejora de la docencia en la asignatura Bioquímica Humana
(Universidad de Sevilla, 2018)
Se presenta una experiencia de mejora en la asignatura Bioquímica Humana en el Grado en Bioquímica, en concreto en dos temas teóricos de la asignatura. En este trabajo se propone un cambio en el modelo metodológico ...
Artículo
Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cell
(2019-10-02)
The placental stem cells have called the focus of attention for their therapeutic potential to treat diferent diseases, including cancer. There is plenty evidence about the antiproliferative, antiangiogenic and ...