Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por agencia financiadora "Universidad de Sevilla"
Mostrando ítems 1-20 de 20
-
Artículo
A putative RNA binding protein from Plasmodium vivax apicoplast
(Wiley, 2018)Malaria is caused by Apicomplexa protozoans from the Plasmodium genus entering the bloodstream of humans and animals through ...
-
Artículo
Biodegradable particles for protein delivery: estimation of the release kinetics inside cells
(Elsevier, 2022-08)A methodology to quantify the efficiency of the protein loading and in-vitro delivery for biodegradable capsules with ...
-
Artículo
Biological Evaluation of Carbohydrate-based Aprepitant Analogs for Neuroblastoma Treatment
(Elsevier, 2024)Different studies using Aprepitant, a NK1R antagonist currently used as a clinical drug for treating chemotherapy-related ...
-
Artículo
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
(Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
-
Artículo
Development of silica‐based biodegradable submicrometric carriers and investigating their characteristics as in vitro delivery vehicles
(MDPI, 2020)Nanostructured silica (SiO2)-based materials are attractive carriers for the delivery of bioactive compounds into cells. ...
-
Artículo
Electrocatalytic CO2 Reduction with a Binuclear Bis-Terpyridine Pyrazole-Bridged Cobalt Complex
(Wiley-VCH GmbH, 2023)A pyrazole-based ligand substituted with terpyridine groups at the 3 and 5 positions has been synthesized to form the ...
-
Artículo
Exploring Multi-Subsite Binding Pockets in Proteins: DEEP-STD NMR Fingerprinting and Molecular Dynamics Unveil a Cryptic Subsite at the GM1 Binding Pocket of Cholera Toxin B
(Wiley, 2020)Ligand-based NMRtechniquesto studyprotein–ligandinteractionsare potenttoolsin drugdesign.Satura-tiontransfer difference ...
-
Artículo
Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties
(Elsevier, 2023)The unique electronic properties of the fluorine atom make its strategic incorporation into a bioactive compound a very ...
-
Artículo
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
(Royal Society of Chemistry, 2016)Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...
-
Artículo
Important Role of NH-Carbazole in Aryl Amination Reactions Catalyzed by 2-Aminobiphenyl Palladacycles
(American Chemical Society, 2023)2-Aminobiphenyl palladacycles are among the most successful precatalysts for Pd-catalyzed cross-coupling reactions, including ...
-
Artículo
Ligand Postsynthetic Functionalization with Fluorinated Boranes and Implications in Hydrogenation Catalysis
(American Chemical Society, 2023)The incorporation of boron functionalities into transition-metal catalysts has become a promising strategy to improve ...
-
Artículo
Lysosomes: multifunctional compartments ruled by a complex regulatory network
(Wiley, 2022)More than 50 years have passed since Nobel laureate Cristian de Duve described for the first time the presence of tiny ...
-
Artículo
Mechanism of Dihydrogen Splitting by An Apparent Bimetallic Frustrated Lewis Pair based on Ir(III)/Pt(0)
(Wiley-Blackwell, 2023)The incorporation of transition metals into frustrated Lewis pairs (FLPs) offers multiple opportunities for bond activation ...
-
Artículo
Phosphorylation at the disordered N-end makes HuR accumulate and dimerize in the cytoplasm.
(Oxford University Press, 2024-07-05)Human antigen R (HuR) is an RNA binding protein mainly involved in maintaining the stability and controlling the translation ...
-
Artículo
Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β-Cyclodextrin Derivatives
(American Chemical Society, 2023)β-cyclodextrin (βCyD) derivatives equipped with aromatic appendages at the secondary face exhibit tailorable self-assembling ...
-
Artículo
Ruthenium Nanoparticles Stabilized by 1,2,3-Triazolylidene Ligands in the Hydrogen Isotope Exchange of E-H Bonds (E = B, Si, Ge, Sn) Using Deuterium Gas
(Royal Society of Chemistry, 2023)A series of ruthenium nanoparticles (Ru·MIC) stabilized with different mesoionic 1,2,3-triazolylidene (MIC) ligands were ...
-
Artículo
sp2-Iminosugar Azobenzene O-glycosides: Light-sensitive Glycosidase Inhibitors with Unprecedented Tunability and Switching Factors
(Elsevier, 2024)The conventional approach to developing light-sensitive glycosidase activity regulators, involving the combination of a ...
-
Artículo
sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease
(Taylor & Francis, 2022)The late-onset form of Tay-Sachs disease displays when the activity levels of human β-hexosaminidase A (HexA) fall below ...
-
Artículo
Speeding-up the Determination of Protein-Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
(American Chemical Society, 2024-01-02)STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small ...
-
Artículo
Zero-valent ML2complexes of Group 10 Metals Supported by Terphenyl Phosphanes
(Royal Society of Chemistry, 2021)Bulky terphenyl phosphane ligands PMe2Ar′ (Ar′ = terphenyl group) facilitate the isolation of zero-valent bis-phosphane ...