Article
Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp
Author/s | González Mauraza, Nuria Haidee
León González, Antonio José ![]() ![]() ![]() ![]() ![]() ![]() Espartero Sánchez, José Luis ![]() ![]() ![]() ![]() ![]() ![]() Gallego Fernández, Juan Bautista ![]() ![]() ![]() ![]() ![]() ![]() ![]() Sánchez Hidalgo, Marina ![]() ![]() ![]() ![]() ![]() ![]() ![]() Martín Cordero, Carmen ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
Department | Universidad de Sevilla. Departamento de Farmacología Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica |
Publication Date | 2016 |
Deposit Date | 2021-05-12 |
Published in |
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Abstract | The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3-O-methyl-chiro-inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of ... The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3-O-methyl-chiro-inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of R. monosperma, and its structure established on the basis of spectroscopic techniques (1D/2D NMR) and MS. Identification and quantification of pinitol in R. raetam and R. sphaerocarpa were also performed. R. monosperma had the highest concentration of pinitol (2.3%). The presence of pinitol in aqueous extracts of Retama spp. may explain the adaptation of these plants to drought and salinity. Furthermore, pinitol could be considered as a mediator in the anti-inflammatory and hypoglycemic activities of Retama spp., which are traditionally used to treat diabetes. |
Citation | González Mauraza, N.H., León González, A.J., Espartero Sánchez, J.L., Gallego Fernández, J.B., Sánchez Hidalgo, M. y Martín Cordero, C. (2016). Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp. Natural Product Communications, 11 (3), 405-406. |
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