Listar Artículos (Genética) por agencia financiadora "Agencia Estatal de Investigación. España"
Mostrando ítems 1-19 de 19
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Bioavailability and provitamin A activity of neurosporaxanthin in mice
(Nature Publishing Group, 2023-10-20)Various species of ascomycete fungi synthesize the carboxylic carotenoid neurosporaxanthin. The unique chemical structure ...
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BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
(Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
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Controlled Transcription of Regulator Gene carS by Tet-on or by a Strong Promoter Confirms Its Role as a Repressor of Carotenoid Biosynthesis in Fusarium fujikuroi
(MDPI, 2020-12)Carotenoid biosynthesis is a frequent trait in fungi. In the ascomycete Fusarium fujikuroi, the synthesis of the carboxylic ...
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Engineered toxin–intein antimicrobials can selectively target and kill antibiotic-resistant bacteria in mixed populations
(Springer Nature, 2019)Targeted killing of pathogenic bacteria without harming beneficial members of host microbiota holds promise as a strategy ...
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Functional Characterization of Lysophosphatidylcholine: Acyl-CoA Acyltransferase Genes From Sunflower (Helianthus annuus L.)
(MDPI, 2020)Lysophosphatidylcholine acyltransferase (LPCAT, EC 2.3.1.23) is an evolutionarily conserved key enzyme in the Lands cycle ...
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Fusarium photoreceptors
(MDPI, 2023-03-04)Light is an important modulating signal in fungi. Fusarium species stand out as research models for their phytopathogenic ...
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Pervasive transcription enhances the accessibility of H-NS–silenced promoters and generates bistability in Salmonella virulence gene expression
(National Academy of Sciences, 2022)In Escherichia coli and Salmonella, many genes silenced by the nucleoid structuring protein H-NS are activated upon ...
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Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae
(Cold Spring Harbor Laboratory Press, 2019)In Saccharomyces cerevisiae, more than 250 trans-acting factors are involved in the maturation of 40S and 60S ribosomal ...
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Rat1 promotes premature transcription termination at R-loops
(Oxford University Press, 2024-04-24)Certain DNA sequences can adopt a non-B form in the genome that interfere with DNA-templated processes, including ...
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RNA biogenesis and RNA metabolism factors as R-loop suppressors: a hidden role in genome integrity.
(Cold Spring Harbor Laboratory Press, 2024-07)Genome integrity relies on the accuracy of DNA metabolism, but as appreciated for more than four decades, transcription ...
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SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
(CELL PRESS (Elsevier), 2024)During genome duplication, replication forks (RFs) can be stalled by different obstacles or by depletion of replication ...
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Symmetric and asymmetric DNA N6-adenine methylation regulates different biological responses in Mucorales
(Nature Research, 2024-07-18)DNA N6-adenine methylation (6mA) has recently gained importance as an epigenetic modification in eukaryotes. Its function ...
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TDP1 suppresses chromosomal translocations and cell death induced by abortive TOP1 activity during gene transcription
(Nature Research, 2023-11-09)DNA topoisomerase I (TOP1) removes torsional stress by transiently cutting one DNA strand. Such cuts are rejoined by TOP1 ...
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The Beak of Eukaryotic Ribosomes: Life, Work and Miracles
(MDPI, 2024-07-22)Ribosomes are not totally globular machines. Instead, they comprise prominent structural protrusions and a myriad of ...
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The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation
(Taylor & Francis, 2022)The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear ...
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The chromatin network helps prevent cancer-associated mutagenesis at transcription-replication conflicts
(Nature Research, 2023)Genome instability is a feature of cancer cells, transcription being an important source of DNA damage. This is in large ...
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Three Genes Involved in Different Signaling Pathways, carS, wcoA, and acyA, Participate in the Regulation of Fusarin Biosynthesis in Fusarium fujikuroi
(MDPI, 2024)The phytopathogenic fungus Fusarium fujikuroi has a rich secondary metabolism which includes the synthesis of very different ...
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Transcriptional regulation by the velvet protein VE-1 during asexual development in the fungus neurospora crassa.
(American Society for Microbiology, 2022)Asexual reproduction in fungi facilitates the dispersal and colonization of new substrates and, in pathogenic fungi, allows ...
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Type III Secretion Effectors with Arginine N-Glycosyltransferase Activity
(MDPI, 2020)Type III secretion systems are used by many Gram-negative bacterial pathogens to inject proteins, known as effectors, into ...