Artículos (Biología Celular)
Recent Submissions
-
Article
Microglia mitochondrial complex I deficiency during development induces glial dysfunction and early lethality
(Nature, 2024-07-24)Primary mitochondrial diseases (PMDs) are associated with pediatric neurological disorders and are traditionally related ...
-
Article
Changes in the expression of inflammatory genes induced by chronic exercise in the adipose tissue: Differences by sex
(MDPI, 2024)The impact of obesity on adipose tissue function is well acknowledged, but the role of physical exercise in regulating ...
-
Article
Protein sorting upon exit from the endoplasmic reticulum dominates Golgi biogenesis in budding yeast
(Willey, 2023-02-24)Cells sense and control the number and quality of their organelles, but the underlying mechanisms of this regulation are ...
-
Article
Sacha Inchi (Plukenetia volubilis L.) Protein Hydrolysate as a New Ingredient of Functional Foods
(MDPI, 2024)Sacha inchi (Plukenetia volubilis L.) is an under-exploited crop with great potential due to its nutritional and medicinal ...
-
Article
UBE2D3 Facilitates NHEJ by Orchestrating ATM Signalling through Multi-level Control of RNF168
(Springer Nature, 2024)Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation ...
-
Article
Rewiring of the epigenome and chromatin architecture by exogenously induced retinoic acid signaling during zebrafish embryonic development
(Oxford University Press, 2024-04-24)Retinoic acid (RA) is the ligand of RA receptors (RARs), transcription factors that bind to RA response elements. RA ...
-
Article
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
(Public Library of Science, 2024-05-22)The helicase MCM and the ribonucleotide reductase RNR are the complexes that provide the substrates (ssDNA templates and ...
-
Article
Roles of Extracellular Vesicles Associated Non-coding RNAs in Diabetes Mellitus
(Frontiers Media SA, 2022)Extracellular vesicles (EVs), especially exosomes (50 to 150 nm), have been shown to play important roles in a wide range ...
-
Article
Physical Forces and Transient Nuclear Envelope Rupture During Metastasis: The Key for Success?
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)During metastasis, invading tumor cells and circulating tumor cells (CTC) face multiple mechanical challenges during ...
-
Article
NR5A2/LRH-1 Regulates the PTGS2-PGE2-PTGER1 Pathway Contributing to Pancreatic Islet Survival and Function
(Elsevier, 2022)LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets ...
-
Article
The PTGS2/COX2-PGE2 Signaling Cascade in Inflammation: Pro or Anti? A Case Study with Type 1 Diabetes Mellitus
(Ivyspring International Publisher, 2023)Prostaglandins are lipid mediators involved in physiological processes, such as constriction or dilation of blood vessels, ...
-
Article
Metabolic Reprogramming by Acly Inhibition Using SB-204990 Alters Glucoregulation and Modulates Molecular Mechanisms Associated with Aging
(Springer Nature, 2023)ATP-citrate lyase is a central integrator of cellular metabolism in the interface of protein, carbohydrate, and lipid ...
-
Article
Enzyme-Responsive Zr-Based Metal-Organic Frameworks for Controlled Drug Delivery: Taking Advantage of Clickable PEG-Phosphate Ligands
(American Chemical Society, 2023)We report for the first time the controlled drug release from a nanoscale Zr-based metal-organic framework (MOF), UiO-66, ...
-
Article
dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe
(Springer Nature, 2024-05-14)The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in ...
-
Article
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
(Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
-
Article
RENEB Inter-Laboratory Comparison 2021: Inter-Assay Comparison of Eight Dosimetry Assays
(Radiation Research Society, 2023)Tools for radiation exposure reconstruction are required to support the medical management of radiation victims in ...
-
Article
SUMO-activated Target Traps (SATTs) Enable the Identification of a Comprehensive E3-specific SUMO Proteome
(American Association for the Advancement of Science, 2023)Ubiquitin and ubiquitin-like conjugation cascades consist of dedicated E1, E2, and E3 enzymes with E3s providing substrate ...
-
Article
Metabolic Disturbance of High-Saturated Fatty Acid Diet in Cognitive Preservation
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Aging continues to be the main cause of the development of Alzheimer’s, although it has been described that certain chronic ...
-
Article
Impact of Sphingolipids on Protein Membrane Trafficking
(Elsevier, 2023)Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane ...
-
Article
Immediate-release Niacin and a Monounsaturated Fatty Acid-rich Meal on Postprandial Inflammation and Monocyte Characteristics in Men with Metabolic Syndrome
(Elsevier, 2023)Background & aim: When considered separately, long-term immediate-release niacin and fatty meals enriched in monounsaturated ...