Perfil del autor: Calderón Montaño, José Manuel
Datos institucionales
| Nombre | Calderón Montaño, José Manuel |
| Departamento | Farmacología |
| Área de conocimiento | Farmacología |
| Categoría profesional | Profesor Titular de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
46
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Nº visitas
10583
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Nº descargas
34334
| Publicaciones |
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Artículo
 Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Current treatments for patients with metastatic triple negative breast cancer (TNBC) are generally ineffective. This ... |
Artículo
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
(MDPI, 2023)
first_pagesettingsOrder Article Reprints Open AccessArticle Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine ... |
Artículo
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are common dietary constituents with ... |
Artículo
 DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
(Elsevier, 2023)
Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic approaches ... |
Artículo
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer
(MDPI, 2022)
New therapies are needed to improve the low survival rates of patients with metastatic colon cancer. Evidence suggests ... |
Trabajo Fin de Grado
Nuevos tratamientos en estudio del mieloma múltiple
(2022)
El Mieloma Múltiple es una neoplasia hematológica muy compleja y de difícil diagnóstico precoz. La incidencia de esta ... |
Artículo
Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Previously, we reported that MTH1 inhibitors TH588 and TH1579 selectively induce oxidative damage and kill Ras-expressing ... |
Artículo
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
(Elsevier, 2022)
Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ... |
Artículo
Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Targeted therapies with antiangiogenic drugs (e.g., sunitinib) and immune checkpoint inhibitors (e.g., anti-PD-1 antibodies) ... |
Artículo
In vitro anticancer activity and mechanism of action of an aziridinyl galactopyranoside
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
We recently screened a series of new aziridines β-D-galactopyranoside derivatives for selective anticancer activity and ... |
Trabajo Fin de Grado
Avances en el tratamiento de la fibromialgia
(2022)
La fibromialgia es considerada como un síndrome que produce un marcado dolor crónico en el aparato locomotor, y se encuentra ... |
Artículo
pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin
(Elsevier, 2022)
Liposomes (Lip) are useful nanocarriers for drug delivery and cancer nanomedicine because of their ability to efficiently ... |
Trabajo Fin de Grado
Farmacoterapia del cáncer de endometrio metastásico
(2021)
El cáncer de endometrio es el décimo cáncer más frecuente a nivel mundial y el segundo más frecuente a nivel ginecológico. ... |
Artículo
Screening for selective anticancer activity of 65 extracts of plants collected in Western Andalusia, Spain
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Finding cytotoxic drugs with a high selectivity towards cancer cells is crucial to improve the low survival rates of ... |
Artículo
Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Stimulus-responsive liposomes (L) for triggering drug release to the target site are particularly useful in cancer therapy. ... |
Trabajo Fin de Máster
Farmacoterapia del asma bronquial y abordaje desde la oficina de farmacia
(2021)
Antecedentes: El asma es una enfermedad inflamatoria crónica que afecta a las vías respiratorias, que cursa con ... |
Trabajo Fin de Grado
Farmacoterapia de la leucemia linfoblástica aguda
(2021)
A pesar de que la leucemia linfoblástica aguda (LLA) es una enfermedad con una baja incidencia en la población adulta, ... |
Trabajo Fin de Grado
Farmacoterapia de la leucemia linfocítica crónica
(2021)
La Leucemia Linfocítica Crónica se trata de una patología muy heterogénea con un difícil diagnóstico precoz. Esto es debido ... |
Trabajo Fin de Grado
Farmacoterapia del cáncer de tiroides metastásico
(2021)
El cáncer de tiroides es la neoplasia endocrina con mayor número de casos y muertes. En general, presenta un buen pronóstico, ... |
Artículo
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity
(American Chemical Society, 2021)
NK1R antagonists, investigated for the treatment of several pathologies, have shown encouraging results in the treatment ... |
Trabajo Fin de Grado
Tratamientos farmacológicos en estudio del cáncer de vejiga
(2020)
El cáncer de vejiga es una enfermedad grave a nivel mundial debido a que se encuentra entre los 10 tipos de cáncer más ... |
Trabajo Fin de Grado
Farmacoterapia en estudio del cáncer hepático
(2020)
El cáncer de hígado es uno de los tipos de cáncer con mayor incidencia y mortalidad a nivel mundial. Presenta tasas muy ... |
Artículo
Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29
(MDPI, 2020)
Colorectal cancer (CRC) is one of the most common types of cancers and a leading cause of cancer death worldwide. The ... |
Artículo
Meroterpenoids from the Brown Alga Cystoseira usneoides as Potential Anti-Inflammatory and Lung Anticancer Agents
(MDPI, 2020)
The anti-inflammatory and anticancer properties of eight meroterpenoids isolated from the brown seaweed Cystoseira usneoides ... |
Artículo
Screening for selective anticancer activity of plants from Grazalema Natural Park, Spain
(Taylor & Francis, 2019)
Since plants are an important source of anticancer drugs, we have carried out a random screening for selective anticancer ... |
Trabajo Fin de Grado
Terapia del cáncer de pulmón no microcítico
(2019)
El cáncer de pulmón no microcítico es uno de los cánceres con mayor incidencia y mortalidad a nivel mundial. Su elevada ... |
Trabajo Fin de Grado
Terapia del carcinoma de células renales
(2018)
El cáncer renal se encuentra entre los 10 tipos de cánceres más diagnosticados a nivel mundial, representando entre el ... |
Trabajo Fin de Grado
Metabolismo del cáncer como diana terapéutica
(2018)
El cáncer es actualmente una de las enfermedades más prevalentes a nivel mundial. A pesar del avance en el diagnóstico ... |
Artículo
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside
(Wiley, 2018)
Several clinically useful anticancer drugs selectively kill cancer cells by inducing DNA damage; the genomic instability ... |
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)
The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) ... |
Artículo
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
(Elsevier, 2017)
Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that ... |
Artículo
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
(Elsevier, 2017)
A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ... |
Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
(MDPI AG, 2016)
Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ... |
Artículo
Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
(2015)
Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial ... |
Artículo
The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2′-deoxycytidine lesions
(Oxford University Press, 2014)
Decitabine (5-aza-21-deoxycytidine, 5-azadC) is used in the treatment of Myelodysplatic syndrome (MDS) and Acute Myeloid ... |
Artículo
Evaluating the cancer therapeutic potential of cardiac glycosides
(Hindawi Publishing Corporation, 2014)
Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that share a steroid-like structure ... |
Artículo
Sulforaphane homologues: Enantiodivergent synthesis of both enantiomers, activationof the Nrf2 transcription factor and selective cytotoxic activity
(Elsevier, 2014)
Reported is an enantiodivergent approach for the synthesis of both enantiomers of sulforaphane (SFN) homologues with ... |
Tesis Doctoral
Evaluación de nuevas estrategias para el desarrollo de terapias anticancerosas selectivas
(2013)
Evaluación de nuevas estrategias para el desarrollo de terapias anticancerosas selectivas El cáncer es una enfermedad ... |
Artículo
Comment on ‘Quiescence and γH2AX in neuroblastoma are regulated by Ouabain/Na,K-ATPase': ouabain and cáncer
(Nature Publishing Group, 2013)
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Artículo
Vitamin C and the Red Wine Polyphenol Resveratrol - but not Curcumin and the Glycolysis Inhibitors 2- Deoxyglucose, Dichloroacetate and 3-Bromopyruvate - Induce Selective Cytotoxicity against Lung Cancer Cells.
(Biomedical Publisher, 2013)
Cancer statistics show that the most commonly diagnosed cancer in the world is lung cancer, that over 50% of patients ... |
Artículo
Dichloroacetate, 2-Deoxyglucose and a Hydroalcoholic Extract from the Skin of the Fruit of Solanum melongena (Aubergine) Induce Selective Anticancer Activity against Melanoma Cells
(Biomedical Publisher, 2013)
Prognosis of melanoma patients with metastatic disease is very poor. For example, over 95% of melanoma patients with three ... |
Artículo
The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells
(Biomedical Publisher, 2013)
Cardiac glycosides are promising anticancer drugs. We have recently shown that the cardiac glycosides digitoxin, digoxin ... |
Artículo
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells
(Georg Thieme Verlag, 2013)
Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium ... |
Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
(Oxford University Press, 2013)
5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological ... |
Artículo
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
(Biomedical Publisher, 2013)
Numerous epidemiological and preclinical studies suggest that flavonoids may play an important role in the decreased risk ... |
Artículo
Role of the Intracellular pH in the Metabolic Switch between Oxidative Phosphorylation and AerobicGlycolysis - Relevance to Cancer
(Biomedical Publisher, 2011)
Cellular energy in the form of ATP can be produced through oxidative phosphorylation and through glycolysis. Since oxidative ... |