dc.creator | Lai, Lien B. | es |
dc.creator | Bernal Bayard, Pilar | es |
dc.creator | Mohannath, Gireesha | es |
dc.creator | Lai, Stella M. | es |
dc.creator | Gopalan, Venkat | es |
dc.creator | Vioque Peña, Agustín | es |
dc.date.accessioned | 2019-03-22T12:54:28Z | |
dc.date.available | 2019-03-22T12:54:28Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Lai, L.B., Bernal Bayard, P., Mohannath, G., Lai, S.M., Gopalan, V. y Vioque Peña, A. (2011). A functional RNase P protein subunit of bacterial origin in some eukaryotes. Molecular Genetics and Genomics, 286 (5-6), 359-369. | |
dc.identifier.issn | 1617-4615 (impreso) | es |
dc.identifier.issn | 1617-4623 (electrónico) | es |
dc.identifier.uri | https://hdl.handle.net/11441/84574 | |
dc.description.abstract | RNase P catalyzes 5′-maturation of tRNAs. While bacterial RNase P comprises an RNA catalyst and a protein cofactor, the eukaryotic (nuclear) variant contains an RNA and up to ten proteins, all unrelated to the bacterial protein. Unexpectedly, a nuclear-encoded bacterial RNase P protein (RPP) homolog is found in several prasinophyte algae including Ostreococcus tauri. We demonstrate that recombinant O. tauri RPP can functionally reconstitute with bacterial RNase P RNAs (RPRs) but not with O. tauri organellar RPRs, despite the latter’s presumed bacterial origins. We also show that O. tauri PRORP, a homolog of Arabidopsis PRORP-1, displays tRNA 5′-processing activity in vitro. We discuss the implications of the striking diversity of RNase P in O. tauri, the smallest known free-living eukaryote. | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación European Regional Fund BFU2007-60651 | es |
dc.description.sponsorship | Junta de Andalucía P06-CVI-01692 | es |
dc.description.sponsorship | National Science Foundation MCB-0238233 MCB-0843543 | es |
dc.description.sponsorship | European Union ASSEMBLE 227799 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Springer | es |
dc.relation.ispartof | Molecular Genetics and Genomics, 286 (5-6), 359-369. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | RNase P diversity | es |
dc.subject | Prasinophyte | es |
dc.subject | Pre-tRNA processing | es |
dc.title | A functional RNase P protein subunit of bacterial origin in some eukaryotes | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular | es |
dc.relation.projectID | BFU2007-60651 | es |
dc.relation.projectID | P06-CVI-01692 | es |
dc.relation.projectID | 227799 | es |
dc.relation.projectID | MCB-0238233 | es |
dc.relation.projectID | MCB-0843543 | es |
dc.relation.publisherversion | http://dx.doi.org/10.1007/s00438-011-0651-y | es |
dc.identifier.doi | 10.1007/s00438-011-0651-y | es |
idus.format.extent | 11 p. | es |
dc.journaltitle | Molecular Genetics and Genomics | es |
dc.publication.volumen | 286 | es |
dc.publication.issue | 5-6 | es |
dc.publication.initialPage | 359 | es |
dc.publication.endPage | 369 | es |