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Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

 

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Opened Access Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin
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Author: García-Rodríguez, Francisco Javier
Martínez-Fernández, Carmen
Brena, David
Kukhtar, Dmytro
Serrat, Xènia
Nadal, Ernest
Boxem, Mike
Honnen, Sebastian
Miranda Vizuete, Antonio
Villanueva, Alberto
Cerón, Julián
Department: Instituto de Biomedicina de Sevilla (IBIS)
Date: 2018-06-21
Published in: Disease Models and Mechanisms, 11 (6), 033506-1-033506-11.
Document type: Article
Abstract: Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to th...
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Cite: García-Rodríguez, F.J., Martínez-Fernández, C., Brena, D., Kukhtar, D., Serrat, X., Nadal, E.,...,Cerón, J. (2018). Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin. Disease Models and Mechanisms, 11 (6), 033506-1-033506-11.
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URI: https://hdl.handle.net/11441/78208

DOI: 10.1242/dmm.033506

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