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Unprecedented Inhibition of Glycosidase-Catalyzed Substrate Hydrolysis by Nanodiamond-Grafted O-Glycosides

 

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Opened Access Unprecedented Inhibition of Glycosidase-Catalyzed Substrate Hydrolysis by Nanodiamond-Grafted O-Glycosides
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Author: Siriwardena, A.
Khanal, M.
Barras, Alexandre
Bande, O.
Mena Barragán, Teresa
Ortiz Mellet, Carmen
García Fernández, José Manuel
Boukheroub, R.
Szunerits, S.
Date: 2015
Published in: RSC Advances, 122 (5), 100568-100578.
Document type: Article
Abstract: We report herein the unprecedented finding that α-O-glucosides and also α-O-mannosides, when conjugated on nanodiamond particles (ND), are not only stable towards the hydrolytic action of the corresponding matching glycosidases, but are also endowed...
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Cite: Siriwardena, A., Khanal, M., Barras, A., Bande, O., Mena Barragán, T., Ortiz Mellet, C.,...,Szunerits, S. (2015). Unprecedented Inhibition of Glycosidase-Catalyzed Substrate Hydrolysis by Nanodiamond-Grafted O-Glycosides. RSC Advances, 122 (5), 100568-100578.
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URI: https://hdl.handle.net/11441/77485

DOI: 10.1039/c5ra21390h

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