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In vitro effect photodynamic therapy with differents photosensitizers on cariogenic microorganisms

Opened Access In vitro effect photodynamic therapy with differents photosensitizers on cariogenic microorganisms

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Autor: Soria Lozano, P.
Gilaberte, Y.
Paz Cristobal, MP.
García Luque, Isabel
Departamento: Universidad de Sevilla. Departamento de Microbiología
Fecha: 2015
Publicado en: BMC Microbiology, 15 (187), 1-7.
Tipo de documento: Artículo
Resumen: Background Antimicrobial photodynamic therapy has been proposed as an alternative to suppress subgingival species. This results from the balance among Streptococcus sanguis, Streptococcus mutans and Candida albicans in the dental biofilm. Not all the photosensitizers have the same photodynamic effect against the different microorganims. The objective of this study is to compare in vitro the photodynamic effect of methylene blue (MB), rose Bengal (RB) and curcumin (CUR) in combination with white light on the cariogenic microorganism S. mutans, S. sanguis and C. albicans. Go to: Results Photodynamic therapy with MB, RB and CUR inhibited 6 log 10 the growth of both bacteria but at different concentrations: 0.31–0.62 μg/ml and 0.62–1.25 μg/ml RB were needed to photoinactivate S. mutans and S. sanguis, respectively; 1.25–2.5 μg/ml MB for both species; whereas higher CUR concentrations (80–160 μg/ml and 160–320 μg/ml) were required to obtain the same reduction in S. mutans and S. sang...
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Cita: Soria Lozano, P., Gilaberte, Y., Paz Cristobal, M. y García Luque, I. (2015). In vitro effect photodynamic therapy with differents photosensitizers on cariogenic microorganisms. BMC Microbiology, 15 (187), 1-7.
Tamaño: 1.159Mb
Formato: PDF

URI: https://hdl.handle.net/11441/75838

DOI: 10.1186/s12866-015-0524-3

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