dc.creator | Martínez Martínez, Luis | es |
dc.creator | García Luque, Isabel | es |
dc.creator | Ballesta Mudarra, Sofía | es |
dc.creator | Benedí, Vicente J. | es |
dc.creator | Hernández Allés, Santiago | es |
dc.creator | Pascual Hernández, Álvaro | es |
dc.date.accessioned | 2017-10-04T16:48:13Z | |
dc.date.available | 2017-10-04T16:48:13Z | |
dc.date.issued | 1998-07-01 | |
dc.identifier.citation | Martínez Martínez, L., García Luque, I., Ballesta Mudarra, S., Benedí, V.J., Hernández Allés, S. y Pascual Hernández, Á. (1998). Energy-dependent accumulation of fluoroquinolones in quinolone- resistant Klebsiella pneumoniae strains. Antimicrobial Agents and Chemotherapy, 42 (7), 1850-1852. | |
dc.identifier.issn | 0066-4804 (impreso) | es |
dc.identifier.issn | 1098-6596 (electrónico) | es |
dc.identifier.uri | http://hdl.handle.net/11441/65006 | |
dc.description.abstract | The intracellular accumulation of norfloxacin and perloxacin in Klebsiella pneumoniae was evaluated. The roles of lipopolysaccharide, capsule, and outer membrane proteins were not important for the intrabacterial accumulation of fluoroquinolones in isogenic strains with known outer membrane alterations. In fluoroquinolone-resistant clinical isolates also expressing GyrA alterations, an active efflux leading to decreased accumulation of the drugs enhanced their resistance to these agents. | es |
dc.description.sponsorship | Comisión Interministerial de Ciencia y Tecnología PB96-0197 | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | American Society for Microbiology | es |
dc.relation.ispartof | Antimicrobial Agents and Chemotherapy, 42 (7), 1850-1852. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.title | Energy-dependent accumulation of fluoroquinolones in quinolone- resistant Klebsiella pneumoniae strains | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Microbiología | es |
dc.relation.projectID | PB96-0197 | es |
idus.format.extent | 3 p. | es |
dc.journaltitle | Antimicrobial Agents and Chemotherapy | es |
dc.publication.volumen | 42 | es |
dc.publication.issue | 7 | es |
dc.publication.initialPage | 1850 | es |
dc.publication.endPage | 1852 | es |
dc.contributor.funder | Comisión Interministerial de Ciencia y Tecnología (CICYT). España | |