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Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain

 

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Opened Access Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain
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Author: Hernández, J. R.
Martínez Martínez, Luis
Cantón, R.
Coque, T. M.
Pascual Hernández, Álvaro
Department: Universidad de Sevilla. Departamento de Microbiología
Date: 2005-05-01
Published in: Antimicrobial Agents and Chemotherapy, 49 (5), 2122-2125.
Document type: Article
Abstract: Clonal dissemination of extended-spectrum -lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae isolates from a nationwide study of 40 Spanish centers in 2000 was not observed in most centers. The most prevalent ESBL were CTX-M-9 (27.3%), SHV-12 (23.9%), and CTX-M-14 (20.5%) for E. coli and TEM-3 (16.7%) and TEM-4 (25%) for K. pneumoniae. A new ESBL, TEM-133, with mutations L21F, E104K, and R164S, was identified.
Cite: Hernández, J.R., Martínez Martínez, L., Cantón, R., Coque, T.M. y Pascual Hernández, Á. (2005). Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain. Antimicrobial Agents and Chemotherapy, 49 (5), 2122-2125.
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URI: http://hdl.handle.net/11441/63342

DOI: 10.1128/AAC.49.5.2122-2125.2005

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