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Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance

Opened Access Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance

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Autor: López Garrido, Javier
Cheng, Nancy
García Quintanilla, Fátima
García del Portillo, Francisco
Casadesús Pursals, Josep
Departamento: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Fecha: 2010
Publicado en: Journal of Bacteriology, 192 (3), 893-895.
Tipo de documento: Artículo
Resumen: The damX gene product of Salmonella enterica serovar Typhimurium is a protein located in the inner membrane. DamX migrates as a 70-kDa protein in SDS-PAGE even though the predicted protein size is 46 kDa. Synthesis of DamX protein occurs in both exponential- and stationary-phase cultures. Disruption of damX causes severe sensitivity to bile. Lack of the outer membrane protein AsmA suppresses bile sensitivity in Salmonella damX mutants.
Cita: López Garrido, J., Cheng, N., García Quintanilla, F., García del Portillo, F. y Casadesús Pursals, J. (2010). Identification of the Salmonella enterica damX gene product, an inner membrane protein involved in bile resistance. Journal of Bacteriology, 192 (3), 893-895.
Tamaño: 248.5Kb
Formato: PDF

URI: http://hdl.handle.net/11441/62901

DOI: 10.1128/JB.01220-09

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