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Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth

 

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Opened Access Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth
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Author: Rallis, Charalampos
López Maury, Luis
Georgescu, Teodora
Pancaldi, Vera
Bähler, Jürg Ürg
Department: Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular
Date: 2014
Published in: Biology Open, 3 (2), 161-171.
Document type: Article
Abstract: Target of rapamycin complex 1 (TORC1), which controls growth in response to nutrients, promotes ageing in multiple organisms. The fission yeast Schizosaccharomyces pombe emerges as a valuable genetic model system to study TORC1 function and cellular...
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Size: 1.264Mb
Format: PDF

URI: http://hdl.handle.net/11441/57475

DOI: 10.1242/bio.20147245

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