Repositorio de producción científica de la Universidad de Sevilla

NADPH-thioredoxin reductase c mediates the response to oxidative stress and thermotolerance in the cyanobacterium anabaena sp. pcc7120

Opened Access NADPH-thioredoxin reductase c mediates the response to oxidative stress and thermotolerance in the cyanobacterium anabaena sp. pcc7120
Estadísticas
Icon
Exportar a
Autor: Sánchez Riego, Ana María
Mata Cabana, Alejandro
Galmozzi, Carla V.
Florencio Bellido, Francisco Javier
Departamento: Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Fecha: 2016
Publicado en: Frontiers in Microbiology, 7 (1283), 1-13.
Tipo de documento: Artículo
Resumen: NADPH-thioredoxin reductase C (NTRC) is a bimodular enzyme composed of an NADPH-thioredoxin reductase and a thiioredoxin domain extension in the same protein. In plants, NTRC has been described to be involved in the protection of the chloroplast against oxidative stress damage through reduction of the 2-Cys peroxiredoxin (2- Cys Prx) as well as through other functions related to redox enzyme regulation. In cyanobacteria, the Anabaena NTRC has been characterized in vitro, however, nothing was known about its in vivo function. In order to study that, we have generated the first knockout mutant strain (LintrC), apart from the previously described in Arabidopsis. Detailed characterization of this strain reveals a differential sensitivity to oxidative stress treatments with respect to the wild-type Anabaena strain, including a higher level of ROS (reactive oxygen species) in normal growth conditions. In the mutant strain, different oxidative stress treatments such as hydrogen peroxide...
[Ver más]
Cita: Sánchez Riego, A.M., Mata Cabana, A., Galmozzi, C.V. y Florencio Bellido, F.J. (2016). NADPH-thioredoxin reductase c mediates the response to oxidative stress and thermotolerance in the cyanobacterium anabaena sp. pcc7120. Frontiers in Microbiology, 7 (1283), 1-13.
Tamaño: 1.778Mb
Formato: PDF

URI: http://hdl.handle.net/11441/49092

Mostrar el registro completo del ítem


Esta obra está bajo una Licencia Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 Internacional

Este registro aparece en las siguientes colecciones