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Adherence to interferon ß-1b treatment in patients with multiple sclerosis in Spain

Opened Access Adherence to interferon ß-1b treatment in patients with multiple sclerosis in Spain
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Autor: Fernández Fernández, Óscar
Izquierdo Ayuso, Guillermo
Agüera, Javier
Millán Pascual, Jorge
Ramió i Torrentà, Lluis
Oliva Nacarino, Pedro
Argente, Javier
Berdei, Yasmina
Soler, José María
Carmona, Olga
Errea, Jose María
Farrés, Jordi
Departamento: Universidad de Sevilla. Departamento de Medicina
Fecha: 2012
Publicado en: PLoS ONE, 7 (5), 1-7.
Tipo de documento: Artículo
Resumen: Background: Adherence to interferon b-1b (INFb-1b) therapy is essential to maximize the beneficial effects of treatment in multiple sclerosis (MS). For that reason, the main objectives of this study are to assess adherence to INFb-1b in patients suffering from MS in Spain, and to identify the factors responsible for adherence in routine clinical practice. Methodology/Principal Findings: This was an observational, retrospective, cross-sectional study including 120 Spanish patients with MS under INFb-1b treatment. Therapeutic adherence was assessed with Morisky-Green test and with the percentage of doses received. The proportion of adherent patients assessed by Morisky-Green test was 68.3%, being indicative of poor adherence. Nevertheless, the percentage of doses received, which was based on the number of injected medication, was 94.3%. The main reason for missing INFb-1b injections was forgetting some of the administrations (64%). Therefore, interventions that diminish forgetfu...
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