Listar Instituto de Biomedicina de Sevilla (IBIS) por título
Mostrando ítems 176-195 de 200
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Targeted Simplification Versus Antipseudomonal Broad-Spectrum Beta-Lactams in Patients With Bloodstream Infections Due to Enterobacteriaceae (SIMPLIFY): A Study Protocol for a Multicentre, Open-Label, Phase III Randomised, Controlled, Non-Inferiority Clinical Trial.
(2017-06-09)Introduction Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one ...
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many ...
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TARTESSUS: a customized electrospun drug delivery system loaded with irinotecan for local and sustained chemotherapy release in pancreatic cancer
(MDPI, 2023)Post-surgical chemotherapy in pancreatic cancer has notorious side effects due to the high dose required. Multiple devices ...
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Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study
(Public Library of Science, 2018-06-28)Background Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. ...
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The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
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The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system
(Springer, 2018-11-29)Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. ...
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The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
(Company of Biologists Limited, 2015-01)Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and ...
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The essential role of IL-17 as the pathogenetic link between psoriasis and metabolic-associated fatty liver disease
(MDPI, 2023)Interleukin 17 (IL-17) is an effector cytokine that plays a key role in the pathogenesis of both psoriasis and ...
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The impact of initial antibiotic treatment failure: Real-world insights in patients with complicated, health care-associated intra-abdominal infection
(Dove, 2019-01-31)Purpose: The RECOMMEND study (NCT02364284; D4280R00005) assessed the clinical management patterns and treatment outcomes ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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The prognosis of patients hospitalized with a first episode of heart failure, validation of two scores: PREDICE and AHEAD
(2019-02-21)Purpose: Heart failure (HF) is a chronic, frequent and disabling condition but with a modifiable course and a large ...
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The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy and safety of an active strategy for the diagnosis and treatment of acute pulmonary embolism during exacerbations of chronic obstructive pulmonary disease.
(2019-02-25)Introduction: Some previous studies have suggested a high prevalence of pulmonary embolism (PE) during exacerbations of ...
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The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease
(Impact Journals LLC, 2016-01-18)Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European ...
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The social impact of Parkinson’s disease in Spain: Report by the Spanish Foundation for the Brain
(Elsevier, 2016)Introduction: Understanding the social and economic impact of Parkinson’s disease is essential for resource planning and ...
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Theory of mind deficits in patients with acquired brain injury: A quantitative review
(Elsevier, 2010)Impaired theory of mind (ToM) reasoning is considered an underlying cause of social cognition deficits in patients with ...
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Trabectedin plus radiotherapy for advanced soft-tissue sarcoma: experience in forty patients treated at a sarcoma reference center
(MDPI, 2020-12-12)Symptomatic control and tumoral shrinkage is an unmet need in advanced soft-tissue sarcoma (STS) patients beyond first-line. ...
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Trait- and state-dependent cortical inhibitory deficits in bipolar disorder
(Wiley, 2016)Objectives Euthymic patients with bipolar disorder (BD) have deficits in cortical inhibition. However, whether cortical ...
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Tremor stability index: a new tool for differential diagnosis in tremor syndromes
(Oxford University Press, 2017)Misdiagnosis among tremor syndromes is common, and can impact on both clinical care and research. To date no validated ...