Listar Instituto de Biomedicina de Sevilla (IBIS) por título
Mostrando ítems 234-253 de 266
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Targeted Simplification Versus Antipseudomonal Broad-Spectrum Beta-Lactams in Patients With Bloodstream Infections Due to Enterobacteriaceae (SIMPLIFY): A Study Protocol for a Multicentre, Open-Label, Phase III Randomised, Controlled, Non-Inferiority Clinical Trial.
(2017-06-09)Introduction Within the context of antimicrobial stewardship programmes, de-escalation of antimicrobial therapy is one ...
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
(Public Library of Science, 2012-05-18)Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many ...
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TARTESSUS: a customized electrospun drug delivery system loaded with irinotecan for local and sustained chemotherapy release in pancreatic cancer
(MDPI, 2023)Post-surgical chemotherapy in pancreatic cancer has notorious side effects due to the high dose required. Multiple devices ...
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Testing for alpha-1 antitrypsin in COPD in outpatient respiratory clinics in Spain: A multilevel, cross-sectional analysis of the EPOCONSUL study
(Public Library of Science, 2018-06-28)Background Alpha-1 antitrypsin deficiency (AATD) is the most common hereditary disorder in adults, but is under-recognized. ...
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The carotid body, a neurogenic niche in the adult peripheral nervous system
(Univ pisa, 2010)We have described a new population of adult neural stem cells residing in the carotid body, a chemoreceptor organ in the ...
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The carotid body: a physiologically relevant germinal niche in the adult peripheral nervous system
(Springer, 2018-11-29)Oxygen constitutes a vital element for the survival of every single cell in multicellular aerobic organisms like mammals. ...
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The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
(Company of Biologists Limited, 2015-01)Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and ...
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The essential role of IL-17 as the pathogenetic link between psoriasis and metabolic-associated fatty liver disease
(MDPI, 2023)Interleukin 17 (IL-17) is an effector cytokine that plays a key role in the pathogenesis of both psoriasis and ...
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The impact of initial antibiotic treatment failure: Real-world insights in patients with complicated, health care-associated intra-abdominal infection
(Dove, 2019-01-31)Purpose: The RECOMMEND study (NCT02364284; D4280R00005) assessed the clinical management patterns and treatment outcomes ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation
(Ferrata Storti Foundation, 2012)Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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The prognosis of patients hospitalized with a first episode of heart failure, validation of two scores: PREDICE and AHEAD
(2019-02-21)Purpose: Heart failure (HF) is a chronic, frequent and disabling condition but with a modifiable course and a large ...
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The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy and safety of an active strategy for the diagnosis and treatment of acute pulmonary embolism during exacerbations of chronic obstructive pulmonary disease.
(2019-02-25)Introduction: Some previous studies have suggested a high prevalence of pulmonary embolism (PE) during exacerbations of ...
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The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease
(Impact Journals LLC, 2016-01-18)Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European ...
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The social impact of Parkinson’s disease in Spain: Report by the Spanish Foundation for the Brain
(Elsevier, 2016)Introduction: Understanding the social and economic impact of Parkinson’s disease is essential for resource planning and ...
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The utility of the macro-aggregated albumin lung perfusion scan in the diagnosis and prognosis of hepatopulmonary syndrome in cirrhotic patients candidates for liver transplantation
(Aran Ediciones S.A., 2017)Background: The macro-aggregated albumin lung perfusion scan (99mTc-MAA) is a diagnostic method for hepatopulmonary ...
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Theory of mind deficits in patients with acquired brain injury: A quantitative review
(Elsevier, 2010)Impaired theory of mind (ToM) reasoning is considered an underlying cause of social cognition deficits in patients with ...
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Therapeutic implications of NK cell regulation of allogeneic CD8 T cell-mediated immune responses stimulated through the direct pathway of antigen presentation in transplantation
(Taylor & Francis, 2018)Natural killer (NK) cells are a population of innate type I lymphoid cells essential for early anti-viral responses and ...
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Trabectedin plus radiotherapy for advanced soft-tissue sarcoma: experience in forty patients treated at a sarcoma reference center
(MDPI, 2020-12-12)Symptomatic control and tumoral shrinkage is an unmet need in advanced soft-tissue sarcoma (STS) patients beyond first-line. ...