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Artículo
Publicaciones médicas: ¿ciencia o negocio?
(Sociedad Española de Investigaciones Óseas y del Metabolismo Mineral, 2016)
En los últimos años ha aumentado enormemente el número de revistas científicas, de tal manera que hoy día es imposible leer ni siquiera el 1% de lo que se publica sobre nuestra especialidad o sobre los campos que nos ...
Artículo
Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer
(Impact Journals, 2016)
DNA methylation is important for gene expression and genome stability, and its disruption is thought to play a key role in the initiation and progression of cancer and other diseases. The DLK1-DIO3 cluster has been shown ...
Artículo
Clinical validation of a real-time polymerase chain reaction assay for rapid detection of Acinetobacter baumannii colonization
(W B SAUNDERS CO LTD, 2016)
Real-time polymerase chain reaction (PCR)-based approaches have not been assessed in terms of their ability to detect patients colonized by Acinetobacter baumannii during active surveillance. This prospective, double-blind ...
Artículo
A randomized clinical trial for remote telemonitoring into an integrated care program for high complexity patients. Atlan-TIC project
(2016)
The use of Information and Communication Technologies (ICT) is a promising development in the XXI century medicine. Its employment has already demonstrated significant benefits in areas such as dermatology or telematic ...
Artículo
Cigarette Smoke Decreases the Maturation of Lung Myeloid Dendritic Cells
(Public Library of Science, 2016-04-08)
Background Conflicting data exist on the role of pulmonary dendritic cells (DCs) and their maturation in patients with chronic obstructive pulmonary disease (COPD). Herein, we investigated whether disease severity and ...
Artículo
Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.
(Impact Journals, 2016-04-20)
Despite the development of new antineoplastic agents for the treatment of colorectal cancer (CRC), oxaliplatin and fluoropyrimidines remain the most commonly employed drugs for the treatment of both early and advanced ...
Artículo
No evidence of firstly acquired acute hepatitis C virus infection outbreak among HIV-infected patients from Southern Spain: a multicentric retrospective study from 2000-2014
(BioMed Central, 2016-09-15)
Background: Acute hepatitis C virus (HCV) infection (AHCVI) outbreaks have been described recently within defined areas worldwide among HIV-infected homosexual men. This study aims to describe the cumulative frequency ...
Artículo
Predictors of Severe Sepsis among Patients Hospitalized for Community-Acquired Pneumonia
(Public Library of Science, 2016-01-04)
Background Severe sepsis, may be present on hospital arrival in approximately one-third of patients with community-acquired pneumonia (CAP). Objective To determine the host characteristics and micro-organisms associated ...
Artículo
Growth rate controls mRNA turnover in steady and non-steady states
(Taylor & Francis, 2016)
Gene expression has been investigated in relation with growth rate in the yeast Saccharomyces cerevisiae, following different experimental strategies. The expression of some specific gene functional categories increases ...
Artículo
Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells
(Public Library Science, 2016)
Obesity is a well-known risk factor for breast cancer development in postmenopausal women. High insulin and leptin levels seem to have a role modulating the growth of these tumours. Sam68 is an RNA-binding protein with ...