Listar Artículos (Fisiología Médica y Biofísica) por título
Mostrando ítems 250-269 de 344
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R-Roscovitine Improves Motoneuron Function in Mouse Models for Spinal Muscular Atrophy
(Elsevier, 2020-02-21)Neurotransmission defects and motoneuron degeneration are hallmarks of spinal muscular atrophy, a monogenetic disease ...
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Rab3D Is Not Required for Exocrine Exocytosis but for Maintenance of Normally Sized Secretory Granules
(2002)Rab3D, a member of the Rab3 subfamily of the Rab/ypt GTPases, is expressed on zymogen granules in the pancreas as well as ...
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Rapamycin restores BDNF-LTP and the persistence of long-term memory in a model of Down's syndrome
(Elsevier, 2015)Down's syndrome (DS) is the most prevalent genetic intellectual disability. Memory deficits significantly contribute to ...
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Rare variants analysis of neurexin-1β in autism reveals a novel start codon mutation affecting protein levels at synapses
(Lippincott, Williams & Wilkins, 2013-08-07)Neurexins are synaptic plasma membrane proteins encoded by three genes (NRXN1, -2, -3) with alternative promoters. Mutations ...
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Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors
(2005)We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric ...
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Rearrangement of cell types in the rat carotid body neurogenic niche induced by chronic intermittent hypoxia
(Wiley, 2023-01-17)The carotid body (CB) is a prototypical acute oxygen (O2)-sensing organ that mediates reflex hyperventilation and increased ...
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Redox signaling in acute oxygen sensing
(Elsevier, 2017-04-26)Acute oxygen (O2) sensing is essential for individuals to survive under hypoxic conditions. The carotid body (CB) is the ...
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Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice
(Nature Publishing Group, 2022)Aging in mammals leads to reduction in genes encoding the 45-subunit mitochondrial electron transport chain complex I. ...
- Otros
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Regulation of oxygen sensing by ion channels
(2004)O2 sensing is of critical importance for cell survival and adaptation of living organisms to changing environments or ...
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Research facilities and highlights at the Centro Nacional de Aceleradores (CNA)
(Springer, 2021)The Centro Nacional de Aceleradores is a user-oriented accelerator facility in Seville, Spain. Its main facilities are a ...
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Resistance of subventricular neural stem cells to chronic hypoxemia despite structural disorganization of the germinal center and impairment of neuronal and oligodendrocyte survival
(Dove Medical Press Ltd., 2015)Chronic hypoxemia, as evidenced in de-acclimatized high-altitude residents or in patients with chronic obstructive ...
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Robustness of PET Radiomics Features: Impact of Co-Registration with MRI
(MDPI, 2021-10-30)Radiomics holds great promise in the field of cancer management. However, the clinical application of radiomics has been ...
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Role of aquaporins in cell proliferation: What else beyond water permeability?
(Taylor & Francis Open Access, 2016-02-21)In addition to the extensive data demonstrating the importance of mammalian AQPs for the movement of water and some small ...
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Role of nitric oxide in gene expression regulation during cancer: epigenetic modifications and non-coding RNAs
(MDPI, 2021-06-10)Nitric oxide (NO) has been identified and described as a dual mediator in cancer according to dose-, time- and ...
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Role of the holoenzyme PP1-SPN in the dephosphorylation of the rb family of tumor suppressors during cell cycle
(MDPI, 2021-05-06)Cell cycle progression is highly regulated by modulating the phosphorylation status of the retinoblastoma protein (pRB) ...
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Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells
(Wiley-Blackwell Publishing Ltd., 2003)Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from ...
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SARAF and EFHB Modulate Store-Operated Ca2+ Entry and Are Required for Cell Proliferation, Migration and Viability in Breast Cancer Cells
(MDPI, 2021)Breast cancer is among the most common malignancies in women. From the molecular point of view, breast cancer can be ...
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SARAF and Orai1 contribute to endothelial cell activation and angiogenesis
(FRONTIERS MEDIA SA, 2021)Angiogenesis is a multistep process that controls endothelial cells (ECs) functioning to form new blood vessels from ...