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Article
Development and validation of an RP-HPLC method for CB13 evaluation in several PLGA nanoparticle systems
(Hindawi Publishing Corporation, 2012)
A simple, fast, and reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for determining of a cannabinoid derivate, which displays potent antihyperalgesic activity, ...
Article
Preparation, characterization and evaluation of the anti-inflammatory activity of epichlorohydrin-β-cyclodextrin/curcumin binary systems embedded in a pluronic® /hyaluronate hydrogel
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Curcumin (Cur) is an anti-inflammatory polyphenol that can be complexed with polymeric cyclodextrin (CD) to improve solubility and bioavailability. The aim of the present work was to prepare a CurCD hydrogel to treat ...
Article
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer
(Universidad de Ciencias Médicas de Tabriz, 2022)
Introduction: Paclitaxel (PTX) is a cornerstone in the treatment of breast cancer, the most common type of cancer in women. However, this drug has serious limitations, including lack of tissue-specificity, poor water ...
Article
Receptor-targeted nanoparticles modulate cannabinoid anticancer activity through delayed cell internalization
(Nature Research, 2022)
Δ9-tetrahydrocannabinol (Δ9-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including low bioavailability, psychotropic side effects ...
Article
Topical Application of Glycolipids from Isochrysis galbana Prevents Epidermal Hyperplasia in Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2018)
Chronic inflammatory skin diseases such as psoriasis have a significant impact on society. Currently, the major topical treatments have many side effects, making their continued use in patients difficult. Microalgae have ...
Article
Trasplante de células naturales "dopaminotróficas" nuevo concepto terapeútico antiparkinsoniano
(Viguera, 2003)
Aim and method. Parkinson's disease is caused by the degeneration of dopamineric neurons of substantia nigra projecting to striatum. Cellular substitution represents a potentially treatment once beneficial levodopa effects ...
Article
Fe-pillared clay mineral-based formulations of imazaquin for reduced leaching in soil
(Elsevier, 2013)
Slow release formulations of the herbicide imazaquin (2-(4-isopropyl-4-methyl-5-oxo-4,5-dihydro-1H-imidazol-2-yl)quinoline-3-carboxylic acid) were prepared by its adsorption on Fe-pillared clay minerals (Fe PILCs). Fe PILCs ...
Article
Development of 3D-Printed Bicompartmental Devices by Dual-Nozzle Fused Deposition Modeling (FDM) for Colon-Specific Drug Delivery.
(MDPI, 2023-09-21)
Dual-nozzle fused deposition modeling (FDM) is a 3D printing technique that allows for the simultaneous printing of two polymeric filaments and the design of complex geometries. Hence, hybrid formulations and structurally ...
Article
Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Systemic lupus erythematosus (SLE) is a chronic immune-inflammatory disease characterized by multiorgan affectation and lowered self-tolerance. Additionally, epigenetic changes have been described as playing a pivotal role ...
Article
Intravitreal, retinal, and central nervous system foscarnet concentrations after rapid intravenous administration to rabbits
(American Society for Microbiology, 2000-03-01)
Retinal, vitreous humor, brain, and cerebrospinal fluid (CSF) foscarnet levels were measured by high-performance liquid chromatography after administration of an intravenous dose of 120 mg/kg of body weight to 32 pigmented ...