Listar Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) por título
Mostrando ítems 257-276 de 284
-
Artículo
Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo
(Elsevier, 2013)Aim Development and evaluation of a new targeted gene delivery system by first preforming self-assembled nanocomplexes ...
-
Artículo
Ten years of FEBS Open Bio
(Wiley, 2021)This month, FEBS Open Bio celebrates its 10th birthday. To celebrate the journal's first decade, we present this special ...
-
Artículo
The Histone Chaperones SET/TAF-1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c-Dependent Manner
(Wiley-Blackwell, 2023)Chromatin homeostasis mediates essential processes in eukaryotes, where histone chaperones have emerged as major regulatory ...
-
Artículo
The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract
(Public Library of Science, 2021)AU The:human Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly gut symbiont Ruminococcus gnavus displays strain-specific ...
-
Artículo
The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study
(2017)The vision of multivalency as a strategy limited to achieve affinity enhancements between a protein receptor and its ...
-
Artículo
The opioid peptide beta-endorphin stimulates acrosome reaction in human spermatozoa
(Wiley-Blackwell, 2016)The acrosome reaction occurs in vivo following sperm capacitation and is essential for the acquisition of sperm fertilization ...
-
Artículo
Therapeutic Efficacy and Biodistribution of Paclitaxel-Bound Amphiphilic Cyclodextrin Nanoparticles: Analyses in 3D Tumor Culture and Tumor-Bearing Animals In Vivo
(MDPI, 2021)The uniqueness of paclitaxel’s antimitotic action mechanism has fueled research toward its application in more effective ...
-
Artículo
Thinking up an original scientific research project
(Turk Biyokimya Dernegi, 2022)Writing a research proposal is not a simple task if we wish-and we do usually wish!-to succeed in putting our project into ...
-
Artículo
Toward a Suitable Structural Analysis of Gene Delivery Carrier Based on Polycationic Carbohydrates by Electron Transfer Dissociation Tandem Mass Spectrometry
(Elsevier, 2016)Polycationic carbohydrates represent an attractive class of biomolecules for several applications and particularly as non ...
-
Artículo
Trehalose- and Glucose-Derived Glycoamphiphiles: Small-Molecule and Nanoparticle Toll-Like Receptor 4 (TLR4) Modulators
(American Chemical Society, 2014)An increasing number of pathologies have been linked to Toll-like receptor 4 (TLR4) activation and signaling, therefore ...
-
Artículo
Trehalose-based Janus cyclooligosaccharides: the Click synthesis and DNA-directed assembly into pH-sensitive transfectious nanoparticles
(Royal Society of Chemistry, 2016)The convergent preparation of Janus molecular nanoparticles by thiourea-‘‘clicking’’ of a,a0 -trehalose halves has been ...
-
Artículo
Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties
(The Society, 2019-06-19)An original family of multivalent vectors encompassing gemini and facial amphiphilicity, namely cationic Siamese twin ...
-
Artículo
Trehalose-polyamine/DNA nanocomplexes: impact of vector architecture on cell and organ transfection selectivity
(Royal Society of Chemistry, 2024-03-05)A novel family of precision-engineered gene vectors with well-defined structures built on trehalose and trehalose-based ...
-
Artículo
Trinuclear copper(I) complexes with triscarbene ligands: catalysis of C–N and C–C coupling reactions
(Royal Society of Chemistry (Great Britain), 2009)Novel synthetic routes for the preparation of trinuclear copper(I) complexes with triscarbene ligands are presented, which ...
-
Artículo
Tuning Activity and Selectivity during Alkyne Activation by Gold(I)/Platinum(0) Frustrated Lewis Pairs
(American Chemical Society, 2020)Introducing transition metals into frustrated Lewis pair systems has attracted considerable attention in recent years. ...
-
Artículo
Unexpected loss of stereoselectivity in glycosylation reactions during the synthesis of chondroitin sulfate oligosaccharides
(Beilstein-Institut, 2019)Here, we present an exploratory study on the fluorous-assisted synthesis of chondroitin sulfate (CS) oligosaccharides. ...
-
Artículo
Unique DC-SIGN clustering activity of a small glycomimetic: a lesson for ligand design
(American Chemical Society, 2014)DC-SIGN is a dendritic cell-specific C-type lectin receptor that recognizes highly glycosylated ligands expressed on the ...
-
Artículo
Unprecedented Inhibition of Glycosidase-Catalyzed Substrate Hydrolysis by Nanodiamond-Grafted O-Glycosides
(Royal Society of Chemistry, 2015)We report herein the unprecedented finding that α-O-glucosides and also α-O-mannosides, when conjugated on nanodiamond ...
-
Artículo
Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Inflammatory processes play a central role in the pathogenesis of diabetic nephropathy (DN) in the early stages of the ...
-
Artículo
Unveiling the Latent Reactivity of Cp* Ligands (C5Me5-) toward Carbon Nucleophiles on an Iridium Complex
(American Chemical Society, 2023)The divergent reactivity of the cationic iridium complex [(η5-C5Me5)IrCl(PMe2ArDipp2)]+ (ArDipp2 = C6H3-2,6-(C6H3-2,6-iPr2)2) ...