Browsing Artículos (Instituto de Investigaciones Químicas (IIQ) – CIC Cartuja) by Title
Now showing items 113-132 of 284
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Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
(Royal Society of Chemistry, 2016)Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking ...
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Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model
(Nature, 2019-02-11)An effective specific immunotherapy should contain elements to generate specific recognition (T-cell peptides) and to ...
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Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery
(Royal Society of Chemistry, 2015)Polycationic amphiphilic cyclodextrins (paCDs) have been shown to behave as efficient non-viral gene carriers paralleling ...
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Helical donor–acceptor platinum complexes displaying dual luminescence and near-infrared circularly polarized luminescence
(Royal Society of Chemistry, 2021)A series of chiral platina[5]helicenes displaying dual luminescence, i.e., fluorescence between 450 and 600 nm and red/NIR ...
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Hemilability of P(X)N-type ligands (X = O, N–H): rollover cyclometalation and benzene C–H activation from (P(X)N)PtMe2 complexes
(Royal Society of Chemistry (Great Britain), 2014)The thermolyses of (tBuP(O)N)PtMe2 (1, tBuP(O)N = (di-tert-butylphosphinito)pyridine) and (tBuP(N–H)N)PtMe2 (3, tBuP(N–H)N ...
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Highly enantioselective hydrogenation of 1-alkylvinyl benzoates: A simple, nonenzymatic access to chiral 2-alkanols
(John Wiley & Sons, 2013)Going chiral! Highly enantioselective catalytic hydrogenations of enol esters 1 by using a Rh catalyst bearing a POP ...
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Highly enantioselective imine hydrogenation catalyzed by ruthenium phosphane-phosphite diamine complexes
(John Wiley & Sons, 2012)Mildly does it: A highly enantioselective catalyst for the hydrogenation of N-aryl imines is described (see scheme). This ...
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Histone chaperone activity of Arabidopsis thaliana NRP1 is blocked by cytochrome c
(Oxford University Press, 2017)Higher-order plants and mammals use similar mechanisms to repair and tolerate oxidative DNA damage. Most studies on the ...
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Article
HIV microbicides: state-of-the-art and new perspectives on the development of entry inhibitors
(Future Science, 2010)Since the discovery of HIV at the beginning of the 1980s, numerous efforts have been devoted to the search of an efficient ...
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Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
(MDPI, 2022)Hepatobiliary tumors are a group of primary malignancies encompassing the liver, the intra- and extra-hepatic biliary ...
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Human dendritic cell activation induced by a permannosylated dendron containing an antigenic GM3-lactone mimetic
(Beilstein-Institut, 2014-06-10)Vaccination strategies based on dendritic cells (DCs) armed with specific tumor antigens have been widely exploited due ...
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HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs
(Oxford University Press, 2019)HuR/ELAVL1 is an RNA-binding protein involved in differentiation and stress response that acts primarily by stabilizing ...
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Hydrazones as Singular Reagents in Asymmetric Organocatalysis
(John Wiley & Sons, 2016)This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric ...
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Hydroboration of carbon dioxide with catechol- and pinacolborane using an Ir–CNP* pincer complex. Water influence on the catalytic activity
(Royal Society of Chemistry, 2018)Iridium complexes based on deprotonated lutidine-derived CNP* pincers 2a/2b selectively catalyzed the hydroboration of ...
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Hydrogenation of an iridium-coordinated imidazol-2-ylidene ligand fragment
(Royal Society of Chemistry, 2018)An iridium complex featuring a metalated lutidine-derived CNP ligand reacts with KOt Bu to yield a dimeric species with ...
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Hydrogenation of imines catalysed by ruthenium(ii) complexes based on lutidine-derived CNC pincer ligands
(Royal Society of Chemistry (Great Britain), 2013)The preparation of new Ru(ii) complexes incorporating fac-coordinated lutidine-derived CNC ligands is reported. These ...
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Identification of a promising multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus
(Elsevier, 2014)DC-SIGN is a C-type lectin receptor on antigen presenting cells (dendritic cells) which has an important role in some viral ...
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Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1
(Oxford University Press, 2014)Heparin-like saccharides play an essential role in binding to the fibroblast growth factor (FGF)-1 and to their membrane ...
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Important Role of NH-Carbazole in Aryl Amination Reactions Catalyzed by 2-Aminobiphenyl Palladacycles
(American Chemical Society, 2023)2-Aminobiphenyl palladacycles are among the most successful precatalysts for Pd-catalyzed cross-coupling reactions, including ...
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Improved non-covalent biofunctionalization of multi-walled carbon nanotubes using carbohydrate amphiphiles with a butterfly-like polyaromatic tail
(Springer, 2010)We have developed an efficient strategy for the non-covalent functionalization of multi-walled carbon nanotubes (MWCNTs) ...