Listar Artículos (Química Orgánica) por título
Mostrando ítems 111-130 de 247
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Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)In recent years, Saturation Transfer Difference NMR (STD NMR) has been proven to be a powerful and versatile ligand-based ...
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Investigation of the Enantioselectivity of Acetylcholinesterase and Butyrylcholinesterase upon Inhibition by Tacrine-iminosugar Heterodimers
(Taylor & Francis, 2023)The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing ...
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Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake
(Elsevier, 2019)In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available ...
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Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes
(American Chemical Society, 2020)A highly regio-, diastereo-, and enantioselective, scalable Ir-catalyzed hydroarylation of electron-rich acyclic and ...
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Iridium-and Palladium-Based Catalysts in the Pharmaceutical Industry
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)Transition metal catalysts play a vital role in a wide range of industrial organic processes. The large-scale production ...
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Isolation and identification of minor secoiridoids and phenolic components from thermally treated olive oil by-products
(Elsevier, 2015-11-15)The application of an industrial process based on the hydrothermal treatment of 160 °C/60 min of alperujo, a by-product ...
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Isolation and X-ray characterization of palladium-N complexes in the guanylation of aromatic amines. Mechanistic implications
(2013)In the context of palladium-catalyzed guanylation of anilines herein, we have been able to characterize and isolate ...
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Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)An increase in the world population and its life expectancy, as well as the ongoing concern about our physical appearance, ...
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Light-Harvesting Properties of a Subphthalocyanine Solar Absorber Coupled to an Optical Cavity
(Wiley-VCH GmbH, 2021-08)Herein, both from the experimental and theoretical point of view, the opticalabsorption properties of a subphthalocyanine ...
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Lipase catalysed kinetic resolution of racemic 1,2-diols containing a chiral quaternary center
(MDPI, 2018)Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic ...
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Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery
(Elsevier, 2011-10)Fully homogeneous facial amphiphiles consisting in a cyclodextrin (CD) platform onto which a polycationic cluster and a ...
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Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of In Vitro Wound-Healing and Anti-Inflammatory Activities
(MDPI, 2020)The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable ...
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Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7
(Nature Research (part of Springer Nature): Fully open access journals, 2019)P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens ...
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Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance
(MDPI, 2020)Cancer accounts for one of the most complex diseases nowadays due to its multifactorial nature. Despite the vast number ...
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Mechanistic Insight into the Binding of Multivalent Pyrrolidines to α-Mannosidases
(Wiley-Blackwell, 2017)Novel pyrrolidine-based multivalent iminosugars, synthesized by a CuAAC approach, have shown remarkable multivalent effects ...
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Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance
(Elsevier, 2021)Drug resistance remains the major cause of cancer treatment failure especially at the late stage of the disease. However, ...
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Molecular Determinants for Cyclo-oligosaccharide-based Nanoparticle-mediated Effective siRNA Transfection
(Future Medicine Ltd., 2017)Aim: To study the structural requirements that a cyclooligosaccharide-based nanoparticle must fulfill to be an efficient ...
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Molecular Recognition of Natural and Non-Natural Substrates by Cellodextrin Phosphorylase from Ruminiclostridium Thermocellum Investigated by NMR Spectroscopy
(Wiley-Blackwell, 2021)β-1→4-Glucan polysaccharides like cellulose, derivatives and analogues, are attracting attention due to their unique ...
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Monosaccharides and Analogues from Simple Achiral Unsaturated Compounds
(Schweizerische Chemische Gesellschaft, 2011)We present herein a selection of ingenious methods that have been developed to convert inexpensive furan, pyrrole and unsaturated hydrocarbons into enantiomerically enriched monosaccharides and analogues of biological interest.