Buscar
Mostrando ítems 31-40 de 135
Artículo
Effect of Statin Therapy in the Outcome of Bloodstream Infections Due to Staphylococcus aureus: A Prospective Cohort Study
(Public Library of Science (PLoS), 2013)
Introduction: Statins have pleiotropic effects that could influence the prevention and outcome of some infectious diseases. There is no information about their specific effect on Staphylococcus aureus bacteremia ...
Artículo
Inhibitor-resistant TEM- And OXA-1-producing Escherichia coli isolates resistant to amoxicillin-clavulanate are more clonal and possess lower virulence gene content than susceptible clinical isolates
(American Society for Microbiology, 2014-01-01)
In a previous prospective multicenter study in Spain, we found that OXA-1 and inhibitor-resistant TEM (IRT) β-lactamases constitute the most common plasmid-borne mechanisms of genuine amoxicillin-clavulanate (AMC) resistance ...
Tesis Doctoral
Estudio de la respuesta clínica al tratamiento antirretroviral en pacientes infectados por subtipos NO-B de VIH-1 mediante la secuenciación de la proteasa retrotranscriptasa e integras: estudio genotípico del T.
(2014-10-01)
En este trabajo se han detallado los datos epidemiológicos de la infección VIH-1 en Andalucía occidental, prestando especial atención a las infecciones por subtipos no- B. Para ello, se ha realizado un análisis de polimorfismos ...
Artículo
Mobile genetic elements related to the diffusion of plasmid-mediated AmpC β-lactamases or carbapenemases from enterobacteriaceae: Findings from a multicenter study in Spain
(American Society for Microbiology, 2015-09-01)
We examined the genetic context of 74 acquired ampC genes and 17 carbapenemase genes from 85 of 640 Enterobacteriaceae isolates collected in 2009. Using S1 pulsed-field gel electrophoresis and Southern hybridization, 37 ...
Artículo
Cost-Effectiveness Analysis of Bezlotoxumab Added to Standard of Care Versus Standard of Care Alone for the Prevention of Recurrent Clostridium difficile Infection in High-Risk Patients in Spain
(Springer, 2018)
Introduction Clostridium difficile infection (CDI) is the major cause of infectious nosocomial diarrhoea and is associated with considerable morbidity, mortality and economic impact. Bezlotoxumab administered in combination ...
Artículo
Long-Term Control of Endemic Hospital-Wide Methicillin-Resistant Staphylococcus aureus (MRSA): The Impact of Targeted Active Surveillance for MRSA in Patients and Healthcare Workers
(Cambridge University Press, 2010-08)
To evaluate the long-term impact of successive interventions on rates of methicillin-resistant Staphylococcus aureus (MRSA) colonization or infection and MRSA bacteremia in an endemic hospital-wide situation. DESIGN:Quas ...
Artículo
Immunization with Lipopolysaccharide-Deficient Whole Cells Provides Protective Immunity in an Experimental Mouse Model of Acinetobacter baumannii Infection
(2014)
The increasing clinical importance of infections caused by multidrug resistant Acinetobacter baumannii warrants the development of novel approaches for prevention and treatment. In this context, vaccination of certain ...
Artículo
Urinary tract physiological conditions promote ciprofloxacin resistance in low-level-quinolone-resistant Escherichia coli
(American Society for Microbiology, 2016-07-01)
Escherichia coli isolates carrying chromosomally encoded low-level-quinolone-resistant (LLQR) determinants are frequently found in urinary tract infections (UTIs). LLQR mutations are considered the first step in the ...
Artículo
Cellular Response to Ciprofloxacin in Low-Level Quinolone-Resistant Escherichia coli
(Frontiers Media, 2017)
Bactericidal activity of quinolones has been related to a combination of DNA fragmentation, reactive oxygen species (ROS) production and programmed cell death (PCD) systems. The underlying molecular systems responsible ...