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Mostrando ítems 1-10 de 21
Tesis Doctoral
Mecanismos de resistencia a Carbapenemas en cepas clínicas de Acinetobacter baumannii
(2001-04-25)
En los últimos años se ha producido un incremento significativo en el número de infecciones nosocomiales causadas por cepas de Acinetobacter baumannii resistentes a carbapenemas. Las opciones terapéuticas en el tratamiento ...
Artículo
Nationwide study of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum β-lactamases in Spain
(American Society for Microbiology, 2005-05-01)
Clonal dissemination of extended-spectrum -lactamases (ESBL) in 170 Escherichia coli isolates and 70 Klebsiella pneumoniae isolates from a nationwide study of 40 Spanish centers in 2000 was not observed in most centers. ...
Artículo
Activities of imipenem and cephalosporins against clonally related strains of Escherichia coli hyperproducing chromosomal β-lactamase and showing altered porin profiles
(American Society for Microbiology, 2000-09-06)
Forty clonally related clinical isolates of Escherichia coli from hospitalized patients were resistant to cefoxitin (MICs, >256 μg/ml) and ceftazidime (MICs, 32 to 256 μg/ml) and were intermediate or resistant to cefotaxime ...
Tesis Doctoral
Resistencia a quinolonas mediada por plásmido en enterobacteriaceae
(2006)
En 1998, se describió por primera vez resistencia a quinolonas transmisible horizontalmente mediante un plásmido conjugativo. La diseminación horizontal de mecanismos de resistencia a fluoroquinolonas abre la posibilidad ...
Artículo
Mutant prevention concentrations of fluoroquinolones for Enterobacteriaceae expressing the plasmid-carried quinolone resistance determinant qnrA1
(American Society for Microbiology, 2007-06-01)
The influence of qnrA1 on the development of quinolone resistance in Enterobacteriaceae was evaluated by using the mutant prevention concentration parameter. The expression of qnrA1 considerably increased the mutant ...
Artículo
Intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes
(American Society for Microbiology, 2006-09-01)
The intracellular penetration and activity of DX-619 in human polymorphonuclear leukocytes have been evaluated. DX-619 reached intracellular concentrations 10 times higher than the extracellular concentrations reached. ...
Tesis Doctoral
Betalactamasas de espectro extendido en enterobacterias aisladas de muestras clínicas de hospitales españoles
(2007-02-06)
En 1985, se describió la primera betalactamasa de espectro extendido (BLEE). En España la primera BLEE fue descrita en 1988. Desde entonces estas betalactamasas se han diseminado por todo el mundo, gracias a la movilidad ...
Artículo
Detection of plasmid-mediated quinolone resistance genes in clinical isolates of Enterobacter spp. in Spain
(American Society for Microbiology, 2009)
We have studied by PCR and DNA sequencing the presence of the qnrA, qnrB, qnrS, aac(6′)-Ib-cr, qepA, intI1, and ISCR1 genes in 200 clinical isolates of Enterobacter cloacae (n = 153) and E. aerogenes (n = 47) consecutively ...
Artículo
Energy-dependent accumulation of norfloxacin and porin expression in clinical isolates of Klebsiella pneumoniae and relationship to extended-spectrum β-lactamase production
(American Society for Microbiology, 2002-12-01)
The relationships between porin deficiency, active efflux of fluoroquinolones, and extended-spectrum β-lactamase (ESBL) production were determined for 53 clinical isolates of Klebsiella pneumoniae. Thirty-two ESBL-positive ...
Artículo
Fatal levofloxacin failure in treatment of a bacteremic patient infected with Streptococcus pneumoniae with a preexisting parC mutation
(American Society for Microbiology, 2008)
The fatal outcome of levofloxacin treatment in a patient with bacteremic pneumonia caused by Streptococcus pneumoniae with a preexisting parC mutation is reported. Failure was due to the emergence of a gyrA mutation after ...