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Mostrando ítems 21-30 de 74
Artículo
Role of the RecBCD recombination pathway in Salmonella virulence
(American Society for Microbiology, 2002)
Mutants of Salmonella enterica lacking the RecBC function are avirulent in mice and unable to grow inside macrophages (N. A. Buchmeier, C. J. Lipps, M. Y. H. So, and F. Heffron, Mol. Microbiol. 7:933-936, 1993). The ...
Artículo
Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA
(Cold Spring Harbor Laboratory Press, 2001)
tmRNA (also known as SsrA or 10Sa RNA) is involved in a trans-translation reaction that contributes to the recycling of stalled ribosomes at the 3′ end of an mRNA lacking a stop codon or at an internal mRNA cluster of rare ...
Artículo
Roles of DNA adenine methylation in host-pathogen interactions: mismatch repair, transcriptional regulation, and more
(Oxford University Press, 2009)
The Dam methylase of gamma-proteobacteria and the CcrM methylase of alpha-proteobacteria catalyze an identical reaction (methylation of adenosine moieties using S-adenosyl-methionine as methyl donor) at similar DNA targets ...
Artículo
Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination
(Nature Publishing Group, 2006)
DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the Smc5–Smc6 ...
Artículo
The GATC-binding protein SeqA is required for bile resistance and virulence in Salmonella enterica serovar Typhimurium
(American Society for Microbiology, 2007)
Disruption of the seqA gene of Salmonella enterica serovar Typhimurium causes defects similar to those described in E. coli: filament formation, aberrant nucleoid segregation, induction of the SOS response, envelope ...
Artículo
YhdJ, a nonessential CcrM-like DNA methyltransferase of Escherichia coli and Salmonella enterica
(American Society for Microbiology, 2007)
The Caulobacter crescentus DNA adenine methyltransferase CcrM and its homologs in the α-Proteobacteria are essential for viability. CcrM is 34% identical to the yhdJ gene products of Escherichia coli and Salmonella enterica. ...
Artículo
The stress-activated protein kinase Hog1 mediates S phase delay in response to osmostress
(American Society for Cell Biology, 2009)
Control of cell cycle progression by stress-activated protein kinases (SAPKs) is essential for cell adaptation to extracellular stimuli. Exposure of yeast to osmostress activates the Hog1 SAPK, which modulates cell cycle ...
Artículo
A new connection of mRNP biogenesis and export with transcription-coupled repair
(Oxford University Press, 2007)
Although DNA repair is faster in the transcribed strand of active genes, little is known about the possible contribution of mRNP biogenesis and export in transcription-coupled repair (TCR). Interestingly, mutants of THO, ...
Artículo
Defective nucleotide excision repair in yeast hpr1 and tho2 mutants
(Oxford University Press, 2002)
Nucleotide excision repair (NER) and transcription are intimately related. First, TFIIH has a dual role in transcription initiation and NER and, secondly, transcription leads to more efficient repair of damage present in ...