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Artículo
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication
(Oxford University Press, 2007)
Homologous recombination (HR) is the major mechanism used to repair double-strand breaks (DSBs) that result from replication, but a study of repair of DSBs specifically induced during S-phase is lacking. Using an inverted-repeat ...
Artículo
Functional analysis of saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis
(Oxford University Press, 2007)
Ribosome synthesis in eukaryotes requires a multitude oftrans-acting factors. These factors act at many steps as the pre-ribosomal particles travel from the nucleolus to the cytoplasm. In contrast to the well-studied ...
Artículo
Microscopic and transcriptome analyses of early colonization of tomato roots by "Trichoderma harzianum".
(Institut d´Estudis Catalans, 2007)
The capacity of the fungus Trichoderma harzianum CECT 2413 to colonize roots and stimulate plant growth was analyzed. Tobacco seedlings (Nicotiana benthamiana) transferred to Petri dishes inoculated with T. harzianum ...
Artículo
The GATC-binding protein SeqA is required for bile resistance and virulence in Salmonella enterica serovar Typhimurium
(American Society for Microbiology, 2007)
Disruption of the seqA gene of Salmonella enterica serovar Typhimurium causes defects similar to those described in E. coli: filament formation, aberrant nucleoid segregation, induction of the SOS response, envelope ...
Artículo
YhdJ, a nonessential CcrM-like DNA methyltransferase of Escherichia coli and Salmonella enterica
(American Society for Microbiology, 2007)
The Caulobacter crescentus DNA adenine methyltransferase CcrM and its homologs in the α-Proteobacteria are essential for viability. CcrM is 34% identical to the yhdJ gene products of Escherichia coli and Salmonella enterica. ...
Artículo
A new connection of mRNP biogenesis and export with transcription-coupled repair
(Oxford University Press, 2007)
Although DNA repair is faster in the transcribed strand of active genes, little is known about the possible contribution of mRNP biogenesis and export in transcription-coupled repair (TCR). Interestingly, mutants of THO, ...
Artículo
Rcs and PhoPQ regulatory overlap in the control of Salmonella enterica virulence
(Journal of Bacteriology, 2007)
Genetic screens based on the use of MudJ-generated lac fusions permitted the identification of novel genes regulated by the Rcs signal transduction system in Salmonella enterica serovar Typhimurium. Besides genes that are ...
Artículo
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex
(National Academy of Sciences, 2007)
Activation-induced cytidine deaminase (AID) is a B cell enzyme essential for Ig somatic hypermutation and class switch recombination. AID acts on ssDNA, and switch regions of Ig genes, a target of AID, form R-loops that ...
Artículo
Characterization of saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis
(American Society for Microbiology, 2007)
We report the characterization of the yeast Npa2p (Urb2p) protein, which is essential for 60S ribosomal subunit biogenesis. We identified this protein in a synthetic lethal screening with thersa3null allele. Rsa3p is a ...