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dc.creatorCasadesús Pursals, Josepes
dc.creatorBeuzón López, Carmen del Rosarioes
dc.creatorChessa, Danielaes
dc.date.accessioned2019-07-03T10:55:52Z
dc.date.available2019-07-03T10:55:52Z
dc.date.issued2004
dc.identifier.citationCasadesús Pursals, J., Beuzón López, C.d.R. y Chessa, D. (2004). IS200: an old and still bacterial transposon. International Microbiology, 7, 1-10.
dc.identifier.issn1618-1905es
dc.identifier.urihttps://hdl.handle.net/11441/87797
dc.description.abstractIS200 is a mobile element found in a variety of eubacterial genera, such as Salmonella, Escherichia, Shigella, Vibrio, Enterococcus, Clostridium, Helicobacter, and Actinobacillus. In addition, IS200-like elements are found in archaea. IS200 elements are very small (707-711 bp) and contain a single gene. Cladograms constructed with IS200 DNA sequences suggest that IS200 has not spread among eubacteria by horizontal transfer; thus it may be an ancestral component of the bacterial genome. Self-restraint may have favored this evolutionary endurance; in fact, unlike typical mobile elements, IS200 transposes rarely. Tight repression of transposase synthesis is achieved by a combination of mechanisms: inefficient transcription, protection from impinging transcription by a transcriptional terminator, and repression of translation by a stem-loop mRNA structure. A consequence of IS200 self-restraint is that the number and distribution of IS200 elements remain fairly constant in natural populations of bacteria. This stability makes IS200 a suitable molecular marker for epidemiological and ecological studies, especially when the number of IS200 copies is high. In Salmonella enterica, IS200 fingerprinting is extensively used for strain discriminationes
dc.description.sponsorshipEspaña University of Seville was supported by a Spanish-Italian Collaborative Grant (Acción Integrada HI2001-0052)es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherSpringer Verlages
dc.relation.ispartofInternational Microbiology, 7, 1-10.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjecttranspositiones
dc.subjectDNA rearrangementses
dc.subjectgenome evolutiones
dc.subjectparasite attenuationes
dc.subjectIS200 fingerprintses
dc.titleIS200: an old and still bacterial transposones
dc.title.alternativeIS200: un antiguo y tranquilo transposón bacterianoes
dc.title.alternativeIS200: um antigo e calmo transposon bacterianoes
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Genéticaes
dc.relation.projectIDAcción Integrada HI2001-0052es
dc.relation.publisherversionhttp://www.im.microbios.org/25march04/02%20Beuzon.pdfes
idus.format.extent10 p.es
dc.journaltitleInternational Microbiologyes
dc.publication.volumen7es
dc.publication.initialPage1es
dc.publication.endPage10es

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