dc.creator | Casadesús Pursals, Josep | es |
dc.creator | Beuzón López, Carmen del Rosario | es |
dc.creator | Chessa, Daniela | es |
dc.date.accessioned | 2019-07-03T10:55:52Z | |
dc.date.available | 2019-07-03T10:55:52Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | Casadesús Pursals, J., Beuzón López, C.d.R. y Chessa, D. (2004). IS200: an old and still bacterial transposon. International Microbiology, 7, 1-10. | |
dc.identifier.issn | 1618-1905 | es |
dc.identifier.uri | https://hdl.handle.net/11441/87797 | |
dc.description.abstract | IS200 is a mobile element found in a variety of eubacterial genera, such as Salmonella, Escherichia, Shigella, Vibrio, Enterococcus, Clostridium, Helicobacter, and Actinobacillus. In addition, IS200-like elements are found in archaea. IS200 elements are very small (707-711 bp) and contain a single gene. Cladograms constructed with IS200 DNA sequences suggest that IS200 has not spread among eubacteria by horizontal transfer; thus it may be an ancestral component of the bacterial genome. Self-restraint may have favored this evolutionary endurance; in fact, unlike typical mobile elements, IS200 transposes rarely. Tight repression of transposase synthesis is achieved by a combination of mechanisms: inefficient transcription, protection from impinging transcription by a transcriptional terminator, and repression of translation by a stem-loop mRNA structure. A consequence of IS200 self-restraint is that the number and distribution of IS200 elements remain fairly constant in natural populations of bacteria. This stability makes IS200 a suitable molecular marker for epidemiological and ecological studies, especially when the number of IS200 copies is high. In Salmonella enterica, IS200 fingerprinting is extensively used for strain discrimination | es |
dc.description.sponsorship | España University of Seville was supported by a Spanish-Italian Collaborative Grant (Acción Integrada HI2001-0052) | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Springer Verlag | es |
dc.relation.ispartof | International Microbiology, 7, 1-10. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | transposition | es |
dc.subject | DNA rearrangements | es |
dc.subject | genome evolution | es |
dc.subject | parasite attenuation | es |
dc.subject | IS200 fingerprints | es |
dc.title | IS200: an old and still bacterial transposon | es |
dc.title.alternative | IS200: un antiguo y tranquilo transposón bacteriano | es |
dc.title.alternative | IS200: um antigo e calmo transposon bacteriano | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Genética | es |
dc.relation.projectID | Acción Integrada HI2001-0052 | es |
dc.relation.publisherversion | http://www.im.microbios.org/25march04/02%20Beuzon.pdf | es |
idus.format.extent | 10 p. | es |
dc.journaltitle | International Microbiology | es |
dc.publication.volumen | 7 | es |
dc.publication.initialPage | 1 | es |
dc.publication.endPage | 10 | es |