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dc.creatorFlores Díaz, Amandoes
dc.creatorGarzón, Andréses
dc.creatorCasadesús Pursals, Josepes
dc.date.accessioned2018-10-11T11:03:52Z
dc.date.available2018-10-11T11:03:52Z
dc.date.issued1992
dc.identifier.citationFlores Díaz, A., Garzón, A. y Casadesús Pursals, J. (1992). Molybdenum cofactor (chlorate-resistant) mutants of Klebsiella pneumoniae M5al can use hypoxanthine as the sole nitrogen source.. journal of bacteriology, 174 (19), 6298-6302.
dc.identifier.issn0021-9193es
dc.identifier.urihttps://hdl.handle.net/11441/79344
dc.description.abstractSelection for chlorate resistance yields mol (formerly chl) mutants with defects in molybdenum cofactor synthesis. Complementation and genetic mapping analyses indicated that the Klebsiella pneumoniae mol genes are functionally homologous to those of Escherichia coli and occupy analogous genetic map positions. Hypoxanthine utilization in other organisms requires molybdenum cofactor as a component of xanthine dehydrogenase, and thus most chlorate-resistant mutants cannot use hypoxanthine as a sole source of nitrogen. Surprisingly, the K. pneumoniae mol mutants and the mol+ parent grew equally well with hypoxanthine as the sole nitrogen source, suggesting that K. pneumoniae has a molybdenum cofactor-independent pathway for hypoxanthine utilization.es
dc.description.sponsorshipEspaña, Junta de Andalucía grant 6-60-609-Bes
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherAmerican Society for Microbiologyes
dc.relation.ispartofjournal of bacteriology, 174 (19), 6298-6302.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleMolybdenum cofactor (chlorate-resistant) mutants of Klebsiella pneumoniae M5al can use hypoxanthine as the sole nitrogen source.es
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Genéticaes
dc.relation.projectIDgrant 6-60-609-Bes
idus.format.extent4 p.es
dc.journaltitlejournal of bacteriologyes
dc.publication.volumen174es
dc.publication.issue19es
dc.publication.initialPage6298es
dc.publication.endPage6302es
dc.contributor.funderJunta de Andalucía

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as: Attribution-NonCommercial-NoDerivatives 4.0 Internacional