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dc.creatorRamírez-López, Pedroes
dc.creatorRos, Abeles
dc.creatorRomero-Arenas, Antonioes
dc.creatorIglesias Sigüenza, Francisco Javieres
dc.creatorFernández Fernández, Rosario Fátimaes
dc.creatorLassaletta, José M.es
dc.date.accessioned2018-06-20T08:39:21Z
dc.date.available2018-06-20T08:39:21Z
dc.date.issued2016
dc.identifier.citationRamírez-López, P., Ros, A., Romero-Arenas, A., Iglesias Sigüenza, F.J., Fernández, R. y Lassaletta, J.M. (2016). Synthesis of IAN-type N,N-Ligands via Dynamic Kinetic Asymmetric Buchwald-Hartwig Amination. Journal of the American Chemical Society, 138 (37), 12053-12056.
dc.identifier.issn0002-7863 (impreso)es
dc.identifier.issn1520-5126 (electrónico)es
dc.identifier.urihttps://hdl.handle.net/11441/76328
dc.description.abstractThe Pd-catalyzed coupling of racemic heterobiaryl bromides, triflates, or nonaflates with aryl/alkyl primary amines using QUINAP as the ligand provides the corresponding axially chiral heterobiaryl amines with excellent yields and enantioselectivities. Reactivity and structural studies of neutral and cationic oxidative addition intermediates support a dynamic kinetic asymmetric amination mechanism based on the labilization of the stereogenic axis in the latter and suggest that coordination of the amine to the Pd center is the stereodetermining step.es
dc.description.sponsorshipMinisterio de Ciencia e Innovación CTQ2013-48164-C2-1-P, CTQ2013-48164-C2-2-P, RYC-2013-12585 for A.R.es
dc.description.sponsorshipEuropean FEDER Fundses
dc.description.sponsorshipJunta de Andalucía 2012/FQM 10787es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherAmerican Chemical Societyes
dc.relation.ispartofJournal of the American Chemical Society, 138 (37), 12053-12056.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleSynthesis of IAN-type N,N-Ligands via Dynamic Kinetic Asymmetric Buchwald-Hartwig Aminationes
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/acceptedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Química Orgánicaes
dc.relation.publisherversionhttp://dx.doi.org/10.1021/jacs.6b07972es
dc.identifier.doi10.1021/jacs.6b07972es
idus.format.extent5es
dc.journaltitleJournal of the American Chemical Societyes
dc.publication.volumen138es
dc.publication.issue37es
dc.publication.initialPage12053es
dc.publication.endPage12056es

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