Artículo
Asymmetric hydrogenation reactions with Rh and Ru complexes bearing phosphine-phosphites with an oxymethylene backbone
Autor/es | Kleman, Patryk Artur
Vaquero Gutiérrez, Mónica Arribas Nieto, Inmaculada Suárez Escobar, Andrés Luis Álvarez González, Eleuterio Pizzano Mancera, Antonio |
Fecha de publicación | 2014 |
Fecha de depósito | 2018-02-06 |
Publicado en |
|
Resumen | Phosphine-phosphites 3a and 3b, derived from diphenylhydroxymethyl phosphine have been prepared. From these ligands [Rh(COD)(3a)]BF4 5a and RuCl2(3b)[(S,S)-DPEN] 6b (DPEN = 1,2-diphenylethylenediamine) were synthesized and ... Phosphine-phosphites 3a and 3b, derived from diphenylhydroxymethyl phosphine have been prepared. From these ligands [Rh(COD)(3a)]BF4 5a and RuCl2(3b)[(S,S)-DPEN] 6b (DPEN = 1,2-diphenylethylenediamine) were synthesized and their structure determined by X-ray diffraction. Ligands 3 are characterized by a small bite angle of 83°. In addition, 5a led to an active catalyst for the hydrogenation of olefins, giving enantioselectivities of up to 96% ee. Likewise, compound 6b showed good activity and enantioselectivity in the hydrogenation of N-1-phenyl ethylidene aniline and a completed reaction at S/C = 500 in 24 h with 83% ee. |
Cita | Kleman, P.A., Vaquero Gutiérrez, M., Arribas Nieto, I., Suárez Escobar, A.L., Álvarez González, E. y Pizzano Mancera, A. (2014). Asymmetric hydrogenation reactions with Rh and Ru complexes bearing phosphine-phosphites with an oxymethylene backbone. Tetrahedron Asymmetry, 25, 744-749. Kleman, P.A., Vaquero Gutiérrez, M., Arribas Nieto, I., Suárez Escobar, A.L., Álvarez González, E. y Pizzano Mancera, A. (2014). Asymmetric hydrogenation reactions with Rh and Ru complexes bearing phosphine-phosphites with an oxymethylene backbone. Tetrahedron Asymmetry, 25, 744-749. |
Ficheros | Tamaño | Formato | Ver | Descripción |
---|---|---|---|---|
Asymmetric hydrogenation react ... | 252.2Kb | [PDF] | Ver/ | |