Show simple item record

dc.creatorBerrougui, Hichames
dc.creatorLópez Lázaro, Migueles
dc.creatorMartín Cordero, Carmenes
dc.creatorMamouchi, Mohamedes
dc.creatorEttaib, Abdelkaderes
dc.creatorHerrera González, María Doloreses
dc.date.accessioned2017-12-13T14:53:27Z
dc.date.available2017-12-13T14:53:27Z
dc.date.issued2005
dc.identifier.citationBerrougui, H., López Lázaro, M., Martín Cordero, C., Mamouchi, M., Ettaib, A. y Herrera González, M.D. (2005). Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.. Journal of Natural Remedies, 5 (1), 41-45.
dc.identifier.issn0972-5547 (impreso)es
dc.identifier.urihttp://hdl.handle.net/11441/67610
dc.description.abstractTo study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated from a methanolic extract from the seeds of P. harmala L. and have been characterized by spectroscopic-Mass and NMR methods. The cytotoxicity of the methanolic extract and both alkaloids has been investigated in the three human cancer cell lines UACC-62 (melanoma), TK-10 (renal) and MCF-7 (breast) and then compared to the positive control effect of the etoposide. Results and conclusion: The methanolic extract and both alkaloids have inhibited the growth of these three cancer cell-lines and we have discussed possible mechanisms involved in their cytotoxicity.es
dc.formatapplication/pdfes
dc.language.isoenges
dc.publisherNatural Remedies Pvt Ltdes
dc.relation.ispartofJournal of Natural Remedies, 5 (1), 41-45.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectPeganum harmalaes
dc.subjectHarminees
dc.subjectHarmalinees
dc.subjectCytotoxicityes
dc.subjectTK-10es
dc.subjectMCF-7es
dc.subjectUACC-62es
dc.titleCytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.es
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Farmacologíaes
idus.format.extent5 p.es
dc.journaltitleJournal of Natural Remedieses
dc.publication.volumen5es
dc.publication.issue1es
dc.publication.initialPage41es
dc.publication.endPage45es
dc.identifier.sisius6630235es

FilesSizeFormatViewDescription
413-413-1-PB.pdf292.5KbIcon   [PDF] View/Open  

This item appears in the following collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Except where otherwise noted, this item's license is described as: Attribution-NonCommercial-NoDerivatives 4.0 Internacional