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Artículo
Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.
dc.creator | Berrougui, Hicham | es |
dc.creator | López Lázaro, Miguel | es |
dc.creator | Martín Cordero, Carmen | es |
dc.creator | Mamouchi, Mohamed | es |
dc.creator | Ettaib, Abdelkader | es |
dc.creator | Herrera González, María Dolores | es |
dc.date.accessioned | 2017-12-13T14:53:27Z | |
dc.date.available | 2017-12-13T14:53:27Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | Berrougui, H., López Lázaro, M., Martín Cordero, C., Mamouchi, M., Ettaib, A. y Herrera González, M.D. (2005). Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L.. Journal of Natural Remedies, 5 (1), 41-45. | |
dc.identifier.issn | 0972-5547 (impreso) | es |
dc.identifier.uri | http://hdl.handle.net/11441/67610 | |
dc.description.abstract | To study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated from a methanolic extract from the seeds of P. harmala L. and have been characterized by spectroscopic-Mass and NMR methods. The cytotoxicity of the methanolic extract and both alkaloids has been investigated in the three human cancer cell lines UACC-62 (melanoma), TK-10 (renal) and MCF-7 (breast) and then compared to the positive control effect of the etoposide. Results and conclusion: The methanolic extract and both alkaloids have inhibited the growth of these three cancer cell-lines and we have discussed possible mechanisms involved in their cytotoxicity. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Natural Remedies Pvt Ltd | es |
dc.relation.ispartof | Journal of Natural Remedies, 5 (1), 41-45. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Peganum harmala | es |
dc.subject | Harmine | es |
dc.subject | Harmaline | es |
dc.subject | Cytotoxicity | es |
dc.subject | TK-10 | es |
dc.subject | MCF-7 | es |
dc.subject | UACC-62 | es |
dc.title | Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L. | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Farmacología | es |
idus.format.extent | 5 p. | es |
dc.journaltitle | Journal of Natural Remedies | es |
dc.publication.volumen | 5 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 41 | es |
dc.publication.endPage | 45 | es |
dc.identifier.sisius | 6630235 | es |
Ficheros | Tamaño | Formato | Ver | Descripción |
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413-413-1-PB.pdf | 292.5Kb | [PDF] | Ver/ | |