dc.creator | Maseda, E. | |
dc.creator | Maggi, G. | |
dc.creator | Gómez-Gil, R. | |
dc.creator | Ruiz, G. | |
dc.creator | Madero, R. | |
dc.creator | García-Perea, A. | |
dc.creator | Aguilar, L. | |
dc.creator | Gilsanz, F. | |
dc.creator | Rodríguez-Baño, Jesús | |
dc.date.accessioned | 2016-02-24T18:20:40Z | |
dc.date.available | 2016-02-24T18:20:40Z | |
dc.date.issued | 2013-02 | |
dc.identifier.citation | Maseda, E., Maggi, G., Gómez-Gil, R., Ruiz, G., Madero, R., García-Perea, A.,...,Rodríguez-Baño, J. (2013). Prevalence of and Risk Factors for Biliary Carriage of Bacteria Showing Worrisome and Unexpected Resistance Traits. | |
dc.identifier.issn | 0095-1137 | es |
dc.identifier.uri | http://hdl.handle.net/11441/36521 | |
dc.description.abstract | Data on biliary carriage of bacteria and, specifically, of bacteria with worrisome and unexpected resistance traits (URB) are lacking.
A prospective study (April 2010 to December 2011) was performed that included all patients admitted for<48 h for elective
laparoscopic cholecystectomy in a Spanish hospital. Bile samples were cultured and epidemiological/clinical data recorded. Logistic
regression models (stepwise) were performed using bactobilia or bactobilia by URB as dependent variables. Models (P<
0.001) showing the highest R2 values were considered. A total of 198 patients (40.4% males; age, 55.3 17.3 years) were included.
Bactobilia was found in 44 of them (22.2%). The presence of bactobilia was associated (R2 Cox, 0.30) with previous biliary endoscopic
retrograde cholangiopancreatography (ERCP) (odds ratio [OR], 8.95; 95% confidence interval [CI], 2.96 to 27.06; P<
0.001), previous admission (OR, 2.82; 95% CI, 1.10 to 7.24; P 0.031), and age (OR, 1.09 per year; 95% CI, 1.05 to 1.12; P<
0.001). Ten out of the 44 (22.7%) patients with bactobilia carried URB: 1 Escherichia coli isolate (CTX-M), 1 Klebsiella pneumoniae
isolate (OXA-48), 3 high-level gentamicin-resistant enterococci, 1 vancomycin-resistant Enterococcus isolate, 3 Enterobacter
cloacae strains, and 1 imipenem-resistant Pseudomonas aeruginosa strain. Bactobilia by URB (versus those by non-URB)
was only associated (R2 Cox, 0.19) with previous ERCP (OR, 11.11; 95% CI, 1.98 to 62.47; P 0.006). For analyses of patients
with bactobilia by URB versus the remaining patients, previous ERCP (OR, 35.284; 95% CI, 5.320 to 234.016; P<0.001), previous
intake of antibiotics (OR, 7.200; 95% CI, 0.962 to 53.906; P 0.050), and age (OR, 1.113 per year of age; 95% CI, 1.028 to
1.206; P 0.009) were associated with bactobilia by URB (R2 Cox, 0.19; P<0.001). Previous antibiotic exposure (in addition to
age and previous ERCP) was a risk driver for bactobilia by URB. This may have implications in prophylactic/therapeutic
measures. | es |
dc.format | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | American Society for Microbiology | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Bilis | es |
dc.subject | Enfermedades de los conductos biliares | es |
dc.subject | Laparoscópica | es |
dc.subject | Factores de riesgo | es |
dc.subject | Farmacorresistencia bacteriana | es |
dc.subject | Prevalencia | es |
dc.subject | Risk Factors | es |
dc.subject | Prevalence | es |
dc.title | Prevalence of and Risk Factors for Biliary Carriage of Bacteria Showing Worrisome and Unexpected Resistance Traits | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | http://jcm.asm.org/content/51/2/518.abstract | es |
dc.identifier.doi | http://dx.doi.org/10.1128/JCM.02469-12 | es |
dc.identifier.idus | https://idus.us.es/xmlui/handle/11441/36521 | |