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Tesis Doctoral
Efectos tóxicos derivados de la ingestión subcrónica de aceite de oliva sometido a diversos grados de fritura en rata
(2016-01-21)
Los productos derivados del calentamiento y oxidación de grasas y aceites que presentan mayor interés son los hidroperóxidos, peróxidos y radicales libres. Estos productos no sólo afectan a la integridad del aceite, sino ...
Artículo
Impact of Gastrointestinal Digestion In Vitro Procedure on the Characterization and Cytotoxicity of Reduced Graphene Oxide
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
The growing interest in graphene derivatives is a result of their variety of applications in many fields. Due to their use, the oral route could be a potential way of entrance for the general population. This work assesses ...
Artículo
In vitro toxicity evaluation of graphene oxide and reduced graphene oxide on Caco-2 cells
(Elsevier, 2022)
Graphene derivatives are expected to have a great impact in a wide range of applications, among them as food packaging materials. This is one of the sources of potential human oral exposure to them. However, studies devoted ...
Artículo
Immunohistochemical approach to study Cylindrospermopsin distribution in tilapia (Oreochromis niloticus) under different exposure conditions
(MDPI, 2014)
Cylindrospermopsin (CYN) is a cytotoxic cyanotoxin produced by several species of freshwater cyanobacteria (i.e., Aphanizomenon ovalisporum). CYN is a tricyclic alkaloid combined with a guanidine moiety. It is well known ...
Artículo
Nuevos riesgos tóxicos por exposición a nanopartículas
(Asociación Española de Toxicología (AETOX), 2009)
La nanotecnología es una ciencia multidisciplinar que está teniendo un gran auge en la actualidad, ya que proporciona productos (nanopartículas) con nuevas propiedades fisicoquímicas, que son las que hacen que tengan ...
Artículo
Toxic Effects of the Cylindrospermopsin and Chlorpyrifos Combination on the Differentiated SH-SY5Y Human Neuroblastoma Cell Line
(Elsevier, 2023)
Due to climate change and anthropogenic activities, the levels of pollution of aquatic and terrestrial environments have increased in the last decades. In this sense, the rise of cyanobacterial blooms, which release secondary ...
Artículo
Influence of refrigeration and freezing in Microcystins and Cylindrospermopsin concentrations on fish muscle of tilapia (Oreochromis niloticus) and tench (Tinca tinca)
(Elsevier, 2021)
The consumption of fish contaminated with cyanotoxins is an important public health issue due to their potential adverse effects. The aim of this study was to assess the influence of refrigeration (4 °C) and freezing (−20 ...
Artículo
In vitro assessment of the combination of cylindrospermopsin and the organophosphate chlorpyrifos on the human neuroblastoma SH-SY5Y cell line
(Elsevier, 2020)
Cylindrospermopsin (CYN) is a cyanotoxicant which occurrence is increasing due to climate change. Cylindrospermopsin is able to exert damage in the organism at several levels, among them, in the nervous system. Moreover, ...
Artículo
Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad
(Real e Ilustre Colegio Oficial de Farmacéuticos de Sevilla, 2023)
Las “Jornadas de divulgación científica: Aportaciones de la Toxicología en la investigación de la seguridad de las sustancias y para la sociedad” se celebraron el 19 de mayo de 2023 en la Facultad de Farmacia de la Universidad ...
Artículo
Neurotoxicity induced by microcystins and cylindrospermopsin: A review
(Elsevier, 2019)
Microcystins (MCs) and cylindrospermopsin (CYN) are among the most frequent toxins produced by cyanobacteria. These toxic secondary metabolites are classified as hepatotoxins and cytotoxin, respectively. Furthermore, both ...