dc.creator | Pérez-Florido, Javier | es |
dc.creator | Casimiro-Soriguer, Carlos S. | es |
dc.creator | Ortuño, Francisco | es |
dc.creator | Fernández-Rueda, José L. | es |
dc.creator | Aguado, Andrea | es |
dc.creator | Lara, María | es |
dc.creator | Lepe Jiménez, José Antonio | es |
dc.date.accessioned | 2024-02-08T13:28:37Z | |
dc.date.available | 2024-02-08T13:28:37Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Pérez-Florido, J., Casimiro-Soriguer, C.S., Ortuño, F., Fernández-Rueda, J.L., Aguado, A., Lara, M. y Lepe Jiménez, J.A. (2023). Detection of high level of co-infection and the emergence of novel SARS CoV-2 delta-omicron and omicron-omicron recombinants in the epidemiological surveillance of Andalusia. International Journal Of Molecular Sciences, 24 (3), 2419. https://doi.org/10.3390/ijms24032419. | |
dc.identifier.issn | 1422-0067 | es |
dc.identifier.uri | https://hdl.handle.net/11441/154944 | |
dc.description.abstract | Recombination is an evolutionary strategy to quickly acquire new viral properties inherited
from the parental lineages. The systematic survey of the SARS-CoV-2 genome sequences of the
Andalusian genomic surveillance strategy has allowed the detection of an unexpectedly high number
of co-infections, which constitute the ideal scenario for the emergence of new recombinants. Whole
genome sequence of SARS-CoV-2 has been carried out as part of the genomic surveillance programme.
Sample sources included the main hospitals in the Andalusia region. In addition to the increase of
co-infections and known recombinants, three novel SARS-CoV-2 delta-omicron and omicron-omicron
recombinant variants with two break points have been detected. Our observations document an
epidemiological scenario in which co-infection and recombination are detected more frequently.
Finally, we describe a family case in which co-infection is followed by the detection of a recombinant
made from the two co-infecting variants. This increased number of recombinants raises the risk of
emergence of recombinant variants with increased transmissibility and pathogenicity | es |
dc.format | application/pdf | es |
dc.format.extent | 11 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | International Journal Of Molecular Sciences, 24 (3), 2419. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | SARS-CoV-2 | es |
dc.subject | Co-infection | es |
dc.subject | Recombination | es |
dc.subject | Surveillance | es |
dc.subject | Epidemiology | es |
dc.title | Detection of high level of co-infection and the emergence of novel SARS CoV-2 delta-omicron and omicron-omicron recombinants in the epidemiological surveillance of Andalusia | es |
dc.type | info:eu-repo/semantics/article | es |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Instituto de Biomedicina de Sevilla (IBIS) | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Microbiología | es |
dc.relation.projectID | PID2020- 117979RB-I00 | es |
dc.relation.projectID | IMP/00019 | es |
dc.relation.projectID | COVID-0012-2020 | es |
dc.relation.projectID | PS-2020-342 | es |
dc.relation.projectID | IE19_259 FPS | es |
dc.relation.publisherversion | https://www.mdpi.com/1422-0067/24/3/2419 | es |
dc.identifier.doi | 10.3390/ijms24032419 | es |
dc.journaltitle | International Journal Of Molecular Sciences | es |
dc.publication.volumen | 24 | es |
dc.publication.issue | 3 | es |
dc.publication.initialPage | 2419 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación de España | es |
dc.contributor.funder | Instituto de Salud Carlos III | es |
dc.contributor.funder | Consejería de Salud y Familias, Junta de Andalucía | es |