Artículo
Low-frequency electrokinetics in a periodic pillar array for particle separation
Autor/es | Calero Martín, Víctor
Fernández Mateo, Raúl Morgan, Hywel García Sánchez, Pablo Ramos Reyes, Antonio |
Departamento | Universidad de Sevilla. Departamento de Electrónica y Electromagnetismo |
Fecha de publicación | 2023 |
Fecha de depósito | 2023-09-06 |
Publicado en |
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Resumen | Deterministic Lateral Displacement (DLD) exploits periodic arrays of pillars inside microfluidic channels for high-precision sorting of micro- and nano-particles. Previously we demonstrated how DLD separation can be ... Deterministic Lateral Displacement (DLD) exploits periodic arrays of pillars inside microfluidic channels for high-precision sorting of micro- and nano-particles. Previously we demonstrated how DLD separation can be significantly improved by the addition of AC electrokinetic forces, increasing the tunability of the technique and expanding the range of applications. At high frequencies of the electric field (>1 kHz) the behaviour of such systems is dominated by Dielectrophoresis (DEP), whereas at low frequencies the particle behaviour is much richer and more complex. In this article, we present a detailed numerical analysis of the mechanisms governing particle motion in a DLD micropillar array in the presence of a low-frequency AC electric field. We show how a combination of Electrophoresis (EP) and Concentration-Polarisation Electroosmosis (CPEO) driven wall-particle repulsion account for the observed experimental behaviour of particles, and demonstrate how this complete model can predict conditions that lead to electrically induced deviation of particles much smaller than the critical size of the DLD array. |
Agencias financiadoras | Junta de Andalucía |
Identificador del proyecto | P20-00534 |
Cita | Calero Martín, V., Fernández Mateo, R., Morgan, H., García Sánchez, P. y Ramos Reyes, A. (2023). Low-frequency electrokinetics in a periodic pillar array for particle separation. Journal of Chromatography A, 1706, 464240. https://doi.org/10.1016/j.chroma.2023.464240. |
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