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dc.creatorGarcía Castillo, E.es
dc.creatorAlonso Pérez, T.es
dc.creatorAncochea, J.es
dc.creatorPastor Sanz, M. T.es
dc.creatorAlmagro, P.es
dc.creatorMartínez-Camblor, P.es
dc.creatorAlfageme Michavila, Inmaculadaes
dc.creatorLópez-Campos Bodineau, José Luises
dc.creatorSoriano, J. Bes
dc.date.accessioned2023-07-12T09:47:35Z
dc.date.available2023-07-12T09:47:35Z
dc.date.issued2020
dc.identifier.citationGarcía Castillo, E., Alonso Pérez, T., Ancochea, J., Pastor Sanz, M.T., Almagro, P., Martínez-Camblor, P.,...,Soriano, J.B. (2020). Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient data. ERJ Open Research, 6 (4), 00253-2020. https://doi.org/10.1183/23120541.00253-2020.
dc.identifier.issn2312-0541es
dc.identifier.urihttps://hdl.handle.net/11441/147899
dc.description.abstractIn 2019, The Global Initiative for Chronic Obstructive Lung Disease (GOLD) modified the grading system for patients with COPD, creating 16 subgroups (1A–4D). As part of the COPD Cohorts Collaborative International Assessment (3CIA) initiative, we aim to compare the mortality prediction of the 2015 and 2019 COPD GOLD staging systems. We studied 17 139 COPD patients from the 3CIA study, selecting those with complete data. Patients were classified by the 2015 and 2019 GOLD ABCD systems, and we compared the predictive ability for 5-year mortality of both classifications. In total, 17 139 patients with COPD were enrolled in 22 cohorts from 11 countries between 2003 and 2017; 8823 of them had complete data and were analysed. Mean±sd age was 63.9±9.8 years and 62.9% were male. GOLD 2019 classified the patients in milder degrees of COPD. For both classifications, group D had higher mortality. 5-year mortality did not differ between groups B and C in GOLD 2015; in GOLD 2019, mortality was greater for group B than C. Patients classified as group A and B had better sensitivity and positive predictive value with the GOLD 2019 classification than GOLD 2015. GOLD 2015 had better sensitivity for group C and D than GOLD 2019. The area under the curve values for 5-year mortality were only 0.67 (95% CI 0.66–0.68) for GOLD 2015 and 0.65 (95% CI 0.63–0.66) for GOLD 2019. The new GOLD 2019 classification does not predict mortality better than the previous GOLD 2015 system.es
dc.formatapplication/pdfes
dc.format.extent10 pág.es
dc.language.isoenges
dc.publisherEuropean Respiratory Societyes
dc.relation.ispartofERJ Open Research, 6 (4), 00253-2020.
dc.rightsAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectCopd patientses
dc.subjectClassificationes
dc.subjectDisabilityes
dc.subjectValidityes
dc.subjectOutcomeses
dc.subjectAsthmaes
dc.titleMortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2015 and GOLD 2019 staging: a pooled analysis of individual patient dataes
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Medicinaes
dc.relation.publisherversionhttps://openres.ersjournals.com/content/6/4/00253-2020es
dc.identifier.doi10.1183/23120541.00253-2020es
dc.journaltitleERJ Open Researches
dc.publication.volumen6es
dc.publication.issue4es
dc.publication.initialPage00253-2020es

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