dc.creator | Muñoz Terol, José Manuel | es |
dc.creator | Rocha Castilla, José Luis | es |
dc.creator | Castro-de la Nuez, Pablo | es |
dc.creator | García Cabrera, Emilio | es |
dc.creator | Vilches Arenas, Ángel | es |
dc.date.accessioned | 2023-05-29T13:19:45Z | |
dc.date.available | 2023-05-29T13:19:45Z | |
dc.date.issued | 2023 | |
dc.identifier.citation | Muñoz Terol, J.M., Rocha Castilla, J.L., Castro-de la Nuez, P., García Cabrera, E. y Vilches Arenas, Á. (2023). Years of potential life lost on renal replacement therapy: retrospective study cohort. JOURNAL OF CLINICAL MEDICINE, 12 (1), 51. https://doi.org/10.3390/jcm12010051. | |
dc.identifier.issn | 2077-0383 | es |
dc.identifier.uri | https://hdl.handle.net/11441/146749 | |
dc.description.abstract | Chronic kidney disease is the non-communicable disease with the highest
growth in morbidity and mortality. Renal transplantation (RT) is the first option of renal replacement
in end-stage kidney disease (ESKD) and dialysis is an alternative. However, there is no objective
quantification of the impact of both options on a patient’s overall survival. The purpose of our
study is to assess the potential years of life lost by patients on renal replacement therapy. Methods:
Retrospective study cohort conducted from 2008 to 2018 based on autonomic data registry. Results:
11,551 patients included who received renal replacement therapy (RRT) in a range of age from 15 to
94 years. The mean age at the time of onset was 62.7 years, 95% confidence interval (95% CI) (62.4;
63.0). The mortality rate of RRT patients was 42.2%, 95% CI (41.5; 43.3) and the mean age at death was
72.7 years, 95% CI (72.4; 73.1). The number of patients with ESKD treated with RT was 3776, 32.7%
of the total, 95% CI (31.8; 33.5). The total amount of years of potential life lost (YPLL) in the entire
cohort was 77,831.3 years, 48,010.1 years in men, and 29,821.2 years in women. The mean number
of YPLL per patient with RRT was 6.74 years in both sexes, 6.95 years in women, and 6.61 years
in men. The mean number of potential years of life lost in dialysis patients was 9.0 years in both
sexes, 8.8 years in men, and 9.2 years in women, while among kidney transplant recipients this figure
decreased to 2.2 years in both men and women. Conclusions: End-stage chronic kidney disease in
renal replacement therapy by dialysis causes an average of 9.0 years of life potentially lost for each
patient on dialysis treatment, while having received a kidney transplant reduces this figure by 75.6%. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | JOURNAL OF CLINICAL MEDICINE, 12 (1), 51. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Renal replacement therapy | es |
dc.subject | End-stage kidney disease | es |
dc.subject | Kidney transplantation | es |
dc.subject | Premature mortality | es |
dc.title | Years of potential life lost on renal replacement therapy: retrospective study cohort | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina Preventiva y Salud Pública | es |
dc.relation.publisherversion | https://www.mdpi.com/2077-0383/12/1/51 | es |
dc.identifier.doi | 10.3390/jcm12010051 | es |
dc.journaltitle | JOURNAL OF CLINICAL MEDICINE | es |
dc.publication.volumen | 12 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 51 | es |