dc.creator | López Jiménez, Elena | es |
dc.creator | González Aguilera, Cristina | es |
dc.date.accessioned | 2023-04-17T17:36:12Z | |
dc.date.available | 2023-04-17T17:36:12Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | López Jiménez, E. y González Aguilera, C. (2022). Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease. Genes, 13 (6). https://doi.org/10.3390/genes13061002. | |
dc.identifier.issn | 2073-4425 | es |
dc.identifier.uri | https://hdl.handle.net/11441/144530 | |
dc.description.abstract | Chromatin organization is essential to maintain a correct regulation of gene expression
and establish cell identity. However, during cell division, the replication of the genetic material
produces a global disorganization of chromatin structure. In this paper, we describe the new scientific
breakthroughs that have revealed the nature of the post-replicative chromatin and the mechanisms
that facilitate its restoration. Moreover, we highlight the implications of these chromatin alterations
in gene expression control and their impact on key biological processes, such as cell differentiation,
cell reprogramming or human diseases linked to cell proliferation, such as cancer. | es |
dc.description.sponsorship | Ministerio de Ciencia e Innovación PID2019-105742GA-100, RYC2018-025485-I | es |
dc.format | application/pdf | es |
dc.format.extent | 13 p. | es |
dc.language.iso | eng | es |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es |
dc.relation.ispartof | Genes, 13 (6). | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Chromatin replication | es |
dc.subject | Chromatin organization | es |
dc.subject | Cell identity | es |
dc.subject | Transcription regulation | es |
dc.subject | Parental histone recycling | es |
dc.subject | Epigenetic maintenance | es |
dc.title | Role of Chromatin Replication in Transcriptional Plasticity, Cell Differentiation and Disease | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Biología Celular | es |
dc.relation.projectID | PID2019-105742GA-100 | es |
dc.relation.projectID | RYC2018-025485-I | es |
dc.relation.publisherversion | https://doi.org/10.3390/genes13061002 | es |
dc.identifier.doi | 10.3390/genes13061002 | es |
dc.journaltitle | Genes | es |
dc.publication.volumen | 13 | es |
dc.publication.issue | 6 | es |
dc.contributor.funder | Ministerio de Ciencia e Innovación (MICIN). España | es |