dc.creator | Santos García, Diego | es |
dc.creator | Álvarez Sauco, María | es |
dc.creator | Calopa, Matilde | es |
dc.creator | Carrillo, Fátima | es |
dc.creator | Escamilla-Sevilla, Francisco | es |
dc.creator | Freire, Eric | es |
dc.creator | Mir Rivera, Pablo | es |
dc.creator | Sesar Ignacio, Ángel | es |
dc.date.accessioned | 2022-11-30T14:18:53Z | |
dc.date.available | 2022-11-30T14:18:53Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Santos García, D., Álvarez Sauco, M., Calopa, M., Carrillo, F., Escamilla-Sevilla, F., Freire, E.,...,Sesar Ignacio, Á. (2022). MNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practice. Diagnostics, 12 (1), 55. https://doi.org/10.3390/diagnostics12010055. | |
dc.identifier.issn | 2075-4418 | es |
dc.identifier.uri | https://hdl.handle.net/11441/139940 | |
dc.description.abstract | Background and objective: Parkinson’s disease (PD) is a clinically heterogeneous disorder
in which the symptoms and prognosis can be very different among patients. We propose a new simple
classification to identify key symptoms and staging in PD. Patients and Methods: Sixteen movement
disorders specialists from Spain participated in this project. The classification was consensually
approved after a discussion and review process from June to October 2021. The TNM classification
and the National Institutes of Health Stroke Scale (NIHSS) were considered as models in the design.
Results: The classification was named MNCD and included 4 major axes: (1) motor symptoms;
(2) non-motor symptoms; (3) cognition; (4) dependency for activities of daily living (ADL). Motor
axis included 4 sub-axes: (1) motor fluctuations; (2) dyskinesia; (3) axial symptoms; (4) tremor. Four
other sub-axes were included in the non-motor axis: (1) neuropsychiatric symptoms; (2) autonomic
dysfunction; (3) sleep disturbances and fatigue; (4) pain and sensory disorders. According to the
MNCD, 5 stages were considered, from stage 1 (no disabling motor or non-motor symptoms with
normal cognition and independency for ADL) to 5 (dementia and dependency for basic ADL).
Conclusions: A new simple classification of PD is proposed. The MNCD classification includes
4 major axes and 5 stages to identify key symptoms and monitor the evolution of the disease in
patients with PD. It is necessary to apply this proof of concept in a properly designed study | es |
dc.format | application/pdf | es |
dc.format.extent | 14 p. | es |
dc.language.iso | eng | es |
dc.publisher | MDPI | es |
dc.relation.ispartof | Diagnostics, 12 (1), 55. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Cognition | es |
dc.subject | Dependency | es |
dc.subject | Non-motor symptoms | es |
dc.subject | Motor symptoms | es |
dc.subject | Parkinson’s disease | es |
dc.title | MNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practice | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://www.mdpi.com/2075-4418/12/1/55 | es |
dc.identifier.doi | 10.3390/diagnostics12010055 | es |
dc.contributor.group | Universidad de Sevilla. CTS630: Trastornos del movimiento. | es |
dc.journaltitle | Diagnostics | es |
dc.publication.volumen | 12 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 55 | es |