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dc.creatorSantos García, Diegoes
dc.creatorÁlvarez Sauco, Maríaes
dc.creatorCalopa, Matildees
dc.creatorCarrillo, Fátimaes
dc.creatorEscamilla-Sevilla, Franciscoes
dc.creatorFreire, Erices
dc.creatorMir Rivera, Pabloes
dc.creatorSesar Ignacio, Ángeles
dc.date.accessioned2022-11-30T14:18:53Z
dc.date.available2022-11-30T14:18:53Z
dc.date.issued2022
dc.identifier.citationSantos García, D., Álvarez Sauco, M., Calopa, M., Carrillo, F., Escamilla-Sevilla, F., Freire, E.,...,Sesar Ignacio, Á. (2022). MNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practice. Diagnostics, 12 (1), 55. https://doi.org/10.3390/diagnostics12010055.
dc.identifier.issn2075-4418es
dc.identifier.urihttps://hdl.handle.net/11441/139940
dc.description.abstractBackground and objective: Parkinson’s disease (PD) is a clinically heterogeneous disorder in which the symptoms and prognosis can be very different among patients. We propose a new simple classification to identify key symptoms and staging in PD. Patients and Methods: Sixteen movement disorders specialists from Spain participated in this project. The classification was consensually approved after a discussion and review process from June to October 2021. The TNM classification and the National Institutes of Health Stroke Scale (NIHSS) were considered as models in the design. Results: The classification was named MNCD and included 4 major axes: (1) motor symptoms; (2) non-motor symptoms; (3) cognition; (4) dependency for activities of daily living (ADL). Motor axis included 4 sub-axes: (1) motor fluctuations; (2) dyskinesia; (3) axial symptoms; (4) tremor. Four other sub-axes were included in the non-motor axis: (1) neuropsychiatric symptoms; (2) autonomic dysfunction; (3) sleep disturbances and fatigue; (4) pain and sensory disorders. According to the MNCD, 5 stages were considered, from stage 1 (no disabling motor or non-motor symptoms with normal cognition and independency for ADL) to 5 (dementia and dependency for basic ADL). Conclusions: A new simple classification of PD is proposed. The MNCD classification includes 4 major axes and 5 stages to identify key symptoms and monitor the evolution of the disease in patients with PD. It is necessary to apply this proof of concept in a properly designed studyes
dc.formatapplication/pdfes
dc.format.extent14 p.es
dc.language.isoenges
dc.publisherMDPIes
dc.relation.ispartofDiagnostics, 12 (1), 55.
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectCognitiones
dc.subjectDependencyes
dc.subjectNon-motor symptomses
dc.subjectMotor symptomses
dc.subjectParkinson’s diseasees
dc.titleMNCD: A New Tool for Classifying Parkinson’s Disease in Daily Clinical Practicees
dc.typeinfo:eu-repo/semantics/articlees
dcterms.identifierhttps://ror.org/03yxnpp24
dc.type.versioninfo:eu-repo/semantics/publishedVersiones
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.contributor.affiliationUniversidad de Sevilla. Departamento de Medicinaes
dc.relation.publisherversionhttps://www.mdpi.com/2075-4418/12/1/55es
dc.identifier.doi10.3390/diagnostics12010055es
dc.contributor.groupUniversidad de Sevilla. CTS630: Trastornos del movimiento.es
dc.journaltitleDiagnosticses
dc.publication.volumen12es
dc.publication.issue1es
dc.publication.initialPage55es

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