dc.creator | Pallares, Christian | es |
dc.creator | Hernández-Gómez, Cristhian | es |
dc.creator | Appel, Tobías Manuel | es |
dc.creator | Escandón, Kevin | es |
dc.creator | Reyes, Sergio | es |
dc.creator | Salcedo, Soraya | es |
dc.creator | Rodríguez-Baño, Jesús | es |
dc.creator | Villegas, María Virginia | es |
dc.date.accessioned | 2022-11-15T17:28:51Z | |
dc.date.available | 2022-11-15T17:28:51Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Pallares, C., Hernández-Gómez, C., Appel, T.M., Escandón, K., Reyes, S., Salcedo, S.,...,Villegas, M.V. (2022). Impact of antimicrobial stewardship programs on antibiotic consumption and antimicrobial resistance in four Colombian healthcare institutions. BMC INFECTIOUS DISEASES, 22 (1), 420. https://doi.org/10.1186/s12879-022-07410-6. | |
dc.identifier.issn | 1471-2334 | es |
dc.identifier.uri | https://hdl.handle.net/11441/139460 | |
dc.description.abstract | Background: Antimicrobial stewardship programs (ASPs) have become a fundamental pillar in optimizing antimicro‑
bial usage, improving patient care, and reducing antimicrobial resistance (AMR). Herein we evaluated the impact of an
ASP on antimicrobial consumption and AMR in Colombia.
Methods: We designed a retrospective observational study and measured trends in antibiotic consumption and
AMR before and after the implementation of an ASP using interrupted time series analysis over a 4-year period
(24 months before and 24 months after ASP implementation).
Results: ASPs were implemented according to the available resources in each of the institutions. Before ASP imple‑
mentation, there was a trend toward an increase in the antibiotic consumption of all measured antimicrobials
selected. Afterward, an overall decrease in antibiotic consumption was observed. The use of ertapenem and mero‑
penem decreased in hospital wards, while a decrease in the use of ceftriaxone, cefepime, piperacillin/tazobactam,
meropenem, and vancomycin was observed in intensive care units. After ASP implementation, the trend toward an
increase of oxacillin-resistant Staphylococcus aureus, ceftriaxone-resistant Escherichia coli, and meropenem-resistant
Pseudomonas aeruginosa was reversed.
Conclusions: In our study, we showed that ASPs are a key strategy in tackling the emerging threat of AMR and have
a positive impact on antibiotic consumption and resistance. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 p. | es |
dc.language.iso | eng | es |
dc.publisher | Biomed Central LTD | es |
dc.relation.ispartof | BMC INFECTIOUS DISEASES, 22 (1), 420. | |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Antimicrobial stewardship | es |
dc.subject | Antimicrobial stewardship program | es |
dc.title | Impact of antimicrobial stewardship programs on antibiotic consumption and antimicrobial resistance in four Colombian healthcare institutions | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.publisherversion | https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-022-07410-6 | es |
dc.identifier.doi | 10.1186/s12879-022-07410-6 | es |
dc.contributor.group | Universidad de Sevilla. CTS-406: Estudio Enfermedades Infecciosas en la Práctica Clínica. | es |
dc.journaltitle | BMC INFECTIOUS DISEASES | es |
dc.publication.volumen | 22 | es |
dc.publication.issue | 1 | es |
dc.publication.initialPage | 420 | es |