dc.creator | Lazarus, J. V. | es |
dc.creator | Palayew, A. | es |
dc.creator | Carrieri, P. | es |
dc.creator | Ekstedt, M. | es |
dc.creator | Marchesini, G. | es |
dc.creator | Novak, K. | es |
dc.creator | Ratziu, V. | es |
dc.creator | Romero Gómez, Manuel | es |
dc.creator | Anstee, Q. M. | es |
dc.date.accessioned | 2022-11-09T15:08:42Z | |
dc.date.available | 2022-11-09T15:08:42Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Lazarus, J.V., Palayew, A., Carrieri, P., Ekstedt, M., Marchesini, G., Novak, K.,...,Anstee, Q.M. (2021). European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease?. JHEP Reports, 3 (2), 100234. https://doi.org/10.1016/j.jhepr.2021.100234. | |
dc.identifier.issn | 2589-5559 | es |
dc.identifier.uri | https://hdl.handle.net/11441/139186 | |
dc.description.abstract | Background & Aims: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome,
and diabetes, is a highly prevalent emerging condition that can be optimally managed through a multidisciplinary patient centred approach. National preparedness to address NAFLD is essential to ensure that health systems can deliver effective
care. We present a NAFLD Preparedness Index for Europe.
Methods: In June 2019, data were extracted by expert groups from 29 countries to complete a 41-item questionnaire about
NAFLD. Questions were classified into 4 categories: policies/civil society (9 questions), guidelines (16 questions), epidemiology
(4 questions), and care management (12 questions). Based on the responses, national preparedness for each indicator was
classified into low, middle, or high-levels. We then applied a multiple correspondence analysis to obtain a standardised
preparedness score for each country ranging from 0 to 100.
Results: The analysis estimated a summary factor that explained 71.3% of the variation in the dataset. No countries were
found to have yet attained a high-level of preparedness. Currently, the UK (75.5) scored best, although falling within the mid level preparedness band, followed by Spain (56.2), and Denmark (43.4), whereas Luxembourg and Ireland were the lowest
scoring countries with a score of 4.9. Only Spain scored highly in the epidemiology indicator category, whereas the UK was the
only country that scored highly for care management.
Conclusions: The NAFLD Preparedness Index indicates substantial variation between countries’ readiness to address NAFLD.
Notably, even those countries that score relatively highly exhibit deficiencies in key domains, suggesting that structural
changes are needed to optimise NAFLD management and ensure effective public health approaches are in place.
Lay summary: Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and
diabetes, is a highly prevalent condition that can be optimally managed through a multidisciplinary patient-centred approach.
National preparedness to address NAFLD is essential to allow for effective public health measures aimed at preventing disease
while also ensuring that health systems can deliver effective care to affected populations. This study defined preparedness as
having adequate policies and civil society engagement, guidelines, epidemiology, and care management. NAFLD preparedness
was found to be deficient in all 29 countries studied, with great variation among the countries and the 4 categories studied. | es |
dc.format | application/pdf | es |
dc.format.extent | 8 p. | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier BV | es |
dc.relation.ispartof | JHEP Reports, 3 (2), 100234. | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Non-alcoholic fatty liver disease | es |
dc.subject | Liver health | es |
dc.subject | Multiple joint correspondence analysis | es |
dc.subject | Policy preparedness | es |
dc.subject | Health policy | es |
dc.subject | Metabolic-associated fatty liver disease | es |
dc.subject | Non-alcoholic steatohepatitis | es |
dc.subject | Europe | es |
dc.title | European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease? | es |
dc.type | info:eu-repo/semantics/article | es |
dcterms.identifier | https://ror.org/03yxnpp24 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.contributor.affiliation | Universidad de Sevilla. Departamento de Medicina | es |
dc.relation.projectID | CP18/00074 | es |
dc.relation.projectID | CEX2018-000806-S | es |
dc.relation.publisherversion | https://www.sciencedirect.com/science/article/pii/S2589555921000100?via%3Dihub | es |
dc.identifier.doi | 10.1016/j.jhepr.2021.100234 | es |
dc.journaltitle | JHEP Reports | es |
dc.publication.volumen | 3 | es |
dc.publication.issue | 2 | es |
dc.publication.initialPage | 100234 | es |
dc.contributor.funder | Instituto de Salud Carlos III | es |
dc.contributor.funder | Ministerio de Ciencia, Innovación y Universidades de España | es |